Fexofenadine chemical structure
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Allegra

Fexofenadine hydrochloride (brand names include Allegra® and Telfast®) is an antihistamine drug used in the treatment of hayfever and similar allergy symptoms. It was developed as a successor of and alternative to terfenadine, an antihistamine with potentially fatal contraindications. more...

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History

Fexofenadine was developed by Hoechst Marion Roussel (now part of Aventis) and approved by the FDA in 1996. Since that time, it has achieved blockbuster drug status with global sales of $1.87B USD in 2004 (with $1.49B USD coming from the United States).

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Aventis announces approval of extended release Allegra-D
From Journal of Drugs in Dermatology, 1/1/05

A 24-hour extended-release tablet form of fexofenadine HCl (Allegra-D 180 mg) made by Aventis Pharmaceuticals, Inc., was approved by the FDA for the relief of symptoms associated with seasonal allergic rhinitis in adults and children aged 12 years and older. This formulation was developed with aaiPharma using a patented extended release drug delivery technology, ProSlo II[TM] developed by Osmotica Pharmaceuticals. Aventis currently markets twice-daily Allegra-D (fexofenadine HCl 60 mg/pseudoephedrine HCl 120 mg) extended release tablets. Allegra-D 24 Hour is the only approved once daily prescription antihistamine with a decongestant.

COPYRIGHT 2005 Journal of Drugs in Dermatology
COPYRIGHT 2005 Gale Group

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