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Anosmia

Anosmia is the lack of olfaction, or a loss of the sense of smell. It can be either temporary or permanent. A related term, hyposmia refers to a decrease in the ability to smell. Some people may be anosmic for one particular odor. This is called "specific anosmia" and may be genetically based. Anosmia can be diagnosed by doctors by using scratch-n-sniff odor tests or by using commonly available odors such as coffee, lemon, and cinnamon. more...

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It should be emphazised that there are no more than 5 dictinctive tastes: salty, sour, sweet, bitter, and umami. The 10,000 different scents humans usually recognize are lost with the loss of olfaction.

A temporary loss of smell can be caused by a stuffy nose or infection. In contrast, a permanent loss of smell may be caused by death of olfactory receptor neurons in the nose, or by brain injury in which there is damage to the olfactory nerve or damage to brain areas that process smell (see olfactory system). The lack of the sense of smell at birth, usually due to genetic factors, is referred as congenital anosmia. Anosmia may be an early sign of degenerative brain diseases such as Parkinson's disease and Alzheimer's disease. Another specific cause of permanent loss could be from damage to olfactory receptor neurons due to use of zinc based nasal sprays .

While termed as a disability, anosmia is often viewed in the medical field as a trivial problem. However, the condition can have a number of detrimental effects . Patients with anosmia may find food less appetizing. Loss of smell can also be dangerous because it hinders the detection of gas leaks, fire, and spoiled food. The common view of anosmia as trivial can make it more difficult for a patient to receive the same types of medical aid as someone who is blind, deaf, or mute.

Losing an established and sentimental smell memory (e.g. the smell of grass, of a toy, of a grandparent's attic, of a particular book, of loved ones, or of oneself) has been known to cause feelings of depression.

Loss of olfaction may lead to the loss of libido, even to the point of impotency, which often preoccupies younger male Anosmics.

Scientists involved in anosmia research include Richard Doty.

Associated conditions

  • Kallmann syndrome
  • zinc deficiency
  • Parkinson's disease
  • Alzheimer's disease

Read more at Wikipedia.org


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Anosmia
From Gale Encyclopedia of Medicine, 4/6/01 by J. Ricker Polsdorfer

Definition

The term anosmia means lack of the sense of smell. It may also refer to a decreased sense of smell. Ageusia, a companion word, refers to a lack of taste sensation. Patients who actually have anosmia may complain wrongly of ageusia, although they retain the ability to distinguish salt, sweet, sour, and bitter--humans' only taste sensations.

Description

Of the five senses, smell ranks fourth in importance for humans, although it is much more pronounced in other animals. Bloodhounds, for example, can smell an odor a thousand times weaker than humans. Taste, considered the fifth sense, is mostly the smell of food in the mouth. The sense of smell originates from the first cranial nerves (the olfactory nerves), which sit at the base of the brain's frontal lobes, right behind the eyes and above the nose. Inhaled airborne chemicals stimulate these nerves.

There are other aberrations of smell beside a decrease. Smells can be distorted, intensified, or hallucinated. These changes usually indicate a malfunction of the brain.

Causes & symptoms

The most common cause of anosmia is nasal occlusion caused by rhinitis (inflammation of the nasal membranes). If no air gets to the olfactory nerves, smell will not happen. In turn, rhinitis and nasal polyps (growths on nasal membranes) are caused by irritants such as allergens, infections, cigarette smoke, and other air pollutants. Tumors such as nasal polyps can also block the nasal passages and the olfactory nerves and cause anosmia. Head injury or, rarely, certain viral infections can damage or destroy the olfactory nerves.

Diagnosis

It is difficult to measure a loss of smell, and no one complains of loss of smell in just one nostril. So a physician usually begins by testing each nostril separately with a common, non-irritating odor such as perfume, lemon, vanilla, or coffee. Polyps and rhinitis are obvious causal agents a physician looks for. Imaging studies of the head may be necessary in order to detect brain injury, sinus infection, or tumor.

Treatment

Cessation of smoking is the first step. Many smokers who quit discover new tastes so enthusiastically that they immediately gain weight. Attention to reducing exposure to other nasal irritants and treatment of respiratory allergies or chronic upper respiratory infections will be beneficial. Corticosteroids are particularly helpful.

Alternative treatment

Finding and treating the cause of the loss of smell is the first approach in naturopathic medicine. If rhinitis is the cause, treating acute rhinitis with herbal mast cell stabilizers and herbal decongestants can offer some relief as the body heals. If chronic rhinitis is present, this is often related to an environmental irritant or to food allergies. Removal of the causative factors is the first step to healing. Nasal steams with essential oils offer relief of the blockage and tonification of the membranes. Blockages can sometimes be resolved through naso-specific therapy--a way of realigning the nasal cavities. Polyp blockage can be addressed through botanical medicine treatment as well as hydrotherapy. Olfactory nerve damage may not be regenerable. Some olfactory aberrations, like intensified sense of smell, can be resolved using homeopathic medicine.

Prognosis

If nasal inflammation is the cause of anosmia, the chances of recovery are excellent. However, if nerve damage is the cause of the problem, the recovery of smell is much more difficult.

Key Terms

Allergen
Any substance that irritates only those who are sensitive (allergic) to it.
Corticosteroids
Cortisone, prednisone, and related drugs that reduce inflammation.
Rhinitis
Inflammation and swelling of the nasal membranes.
Nasal polyps
Drop-shaped overgrowths of the nasal membranes.

Further Reading

For Your Information

    Books

  • Bennett, J. Claude, and Fred Plum. "Smell and Taste" In Cecil Textbook of Medicine. Philadelphia: W.B. Saunders, 1996, pp. 2014-2015.
  • Isselbacher, Kurt, et al., eds. Harrison's Principles of Internal Medicine. New York: McGraw-Hill, August 1997, pp. 109-110.
  • Tierney Jr., Lawrence M., et al., eds. "Olfactory Dysfunction." In Current Medical Diagnosis and Treatment. Stamford, CT: Appleton & Lange, 1998, p. 232.

    Periodicals

  • Davidson, T.M., C. Murphy, and A.A. Jalowayski. "Smell Impairment. Can It Be Reversed?" Postgraduate Medicine 98 (July 1995): 107-109, 112.

Gale Encyclopedia of Medicine. Gale Research, 1999.

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