Meclizine's chemical structure
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Antivert

Meclizine is an antihistamine, considered to be an antiemetic. It is most commonly used to inhibit nausea and vomiting. An alternative to Dimenhydrinates like Dramamine, Meclizine is considered to perform the same functions at an equitable level of effectiveness, but with reduced side effects. more...

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Uses

Motion Sickness

Meclizine is effective in inhibiting the symptoms of motion sickness, such as nausea, vomiting, and dizziness.

Vertigo

Meclizine may be effective in relieving vertigo experienced as a result of inner ear infections or other conditions.

Risks of Use

Drowsiness

Drowsiness may result as a side effect of taking Meclizine. While the effects are less than Dramamine, users are advised not to operate heavy machinery while under the influence. The consumption of alcohol while under the influence of Meclizine may result in additional drowsiness.

Pregnancy

Studies have shown that cleft palates of fetuses were formed when pregnant rats were exposed to 25-50 times a normal dosage. Nevertheless, pregnant women are advised not to take Meclizine unless it is absolutely necessary.

Anticholinergics

Due to its possible anticholinergic action, Meclizine should be used carefully with patients who suffer from asthma, glaucoma, or an enlarged prostate gland.

Commercial Names

Meclizine hydrochloride is sold under the commercial names

  • Dramamine II®
  • Dramamine Less Drowsy®
  • Antivert®
  • Bonamine®
  • Bonikraft®
  • Emetostop®
  • Medivert®
  • Sea-Legs®

Read more at Wikipedia.org


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The doctor weighs in
From Inside MS, 6/22/01 by Barbara Giesser

What should I do if I have an exacerbation while traveling?.

The first thing to remember is what an exacerbation is. It's a worsening of old symptoms or the appearance of new ones that lasts at least 24 hours. This is important because stress, heat, and/or fatigue (all of which easily happen while traveling) could cause a temporary symptom flare, which should clear by the next day. If symptoms persist, do you have signs of infection? new bladder symptoms? a fever? symptoms of flu or a cold? If there is an infection, have it treated. Your flare may be a pseudoexacerbation.

In the event of a true exacerbation, seek medical evaluation, preferably by a neurologist. However, if you have a predictable response to steroids and you'll be traveling in an area where medical help might not be available, your physician may give you a prescription for a brief (1-2 weeks) supply of oral prednisone to take with you just in case.

I'm pecking my injectables in an insulated carry-on bag, but suppose I can't freeze my Blue Ice?

Avonex, Betaseron, and Copaxone (before they are reconstituted) can stay at temperatures that don't exceed 86 [degrees] for a total of 7 days. Ice can usually be obtained on airplanes, trains, and in hotels.

Remember to pack clean plastic bags for ice holders.

Do I need a note from my neurologist to get through airport security with my needles?

Some airports, particularly overseas, may have more stringent security standards. So, yes, it's safest to have a doctor's note certifying that you are on injectable prescription medication. Additionally, tours or cruise lines may require a "fitness to travel" letter from your doctor.

What do you recommend for diarrhea? motion sickness? or Third World travel?

Over-the-counter anti-diarrheals, such as Kaopectate, Pepto-Bismol, or Imodium, work well. The biggest problem from diarrhea is dehydration. If you are traveling in less-developed areas, it's wise to pack some electrolyte-rich "sports" liquids. Persistent diarrhea, or diarrhea accompanied by fever or abdominal pain that lasts more than a day, needs medical evaluation. Over-the-counter Dramamine works for motion sickness, or your doctor may give you a prescription for Antivert (meclizine). The Centers for Disease Control posts vaccination recommendations for everywhere in the world. Ask your doctor to check their valuable Web site: <www.cdc.gov>.

Barbara Giesser, MD, is a clinical neurologist who has specialized in MS care for more than 20 years; she is chair of the editorial board of this magazine.

COPYRIGHT 2001 National Multiple Sclerosis Society
COPYRIGHT 2002 Gale Group

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