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Augmentin

Co-amoxiclav is the British Approved Name, in the British Pharmacopoeia, for the combination antibiotic containing Amoxicillin (as either trihydate or the sodium salt) and Clavulanic acid (as Potassium clavulanate). This name, unlike co-trimoxazole, has not been widely adopted internationally and the combination product is usually referred to by various names such as amoxicillin with clavulanic acid or amoxicillin+clavulanate or simply by the trade name. more...

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Co-amoxiclav is currently marketed by GlaxoSmithKline under the trade name Augmentin®, and by Pfizer as Clavamox® (Clavamox® is for veterinary use only).

The combination of amoxicillin, a β-lactam antibiotic; with clavulanic acid, a β-lactamase inhibitor; results in an antibiotic with an increased spectrum of action and restored efficacy against β-lactamase producing amoxicillin-resistant bacteria.

Dosage

  • Co-amoxiclav sensitive organisms

Side effects

Amongst the possible side-effects of this medication are diarrhoea, vomiting and a few other conditions. These do not usually require medical attention. However, if the patient experiences an allergic reaction to the medication, jaundice, fever or severe diarrhoea, it is necessary to contact a doctor immediately.

Amoxicillin is a member of the penicillin family of antibiotics, and therefore should not be taken by patients allergic to penicillin.

Read more at Wikipedia.org


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GSK to appeal court ruling - Generics Watch - GlaxoSmithKline plans federal appeal regarding Augmentin ruling - Brief Article
From Drug Store News, 1/21/02

GlaxoSmithKline plans to appeal a federal court ruling that said GSK's patent on the antibiotic Augmentin (amoxicillin/clavulanate potassium) ends in December 2002, not in 2018.

In the summary judgment ruling, the court ruled in GSK's favor that its patent expiring in December 2002 was valid, noted a GSK statement, but ruled in Teva's favor that a GSK patent expiring in 2018 was invalid. Teva is a generic drug company.

GSK said it intends to appeal the court's ruling on the patent expiring in 2018.

In addition to the two patents just ruled on, GSK holds various other patents covering Augmentin in the United States with expiry periods up to 2017. Geneva, another generic drug maker, also is looking to produce Augmentin.

COPYRIGHT 2002 Reproduced with permission of the copyright holder. Further reproduction or distribution is prohibited without permission.
COPYRIGHT 2002 Gale Group

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