Molecular structure of nizatidine
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Axid

Nizatidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). It was developed by Eli Lilly and is marketed under the trade names Tazac and Axid. more...

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Clinical use

Certain preparations of nizatadine are now available over the counter in various countries including the United States.

History and development

Nizatidine was developed by Eli Lilly, and was first marketed in 1987. It is considered to be equipotent with ranitidine and differs by the substitution of a thiazole-ring in place of the furan-ring in ranitidine.

Nazitidine proved to be the last new histamine H2-receptor antagonists introduced prior to the advent of proton pump inhibitors.

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Ivax has been given the nod from the FDA for its abbreviated new drug application for nizatidine capsules, a generic version of Eli Lilly's Axid - Generic
From Drug Store News, 7/22/02 by Jennifer Kovacs

Ivax has been given the nod from the FDA for its abbreviated new drug application for nizatidine capsules, a generic version of Eli Lilly's Axid. Nizatidine, approved in 150 mg and 300 mg strengths, is designed to relieve heartburn, acid indigestion and sour stomach. Sales of Axid in the United States last year were about $233 million.

COPYRIGHT 2002 Reproduced with permission of the copyright holder. Further reproduction or distribution is prohibited without permission.
COPYRIGHT 2002 Gale Group

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