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Bacitracin

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically. more...

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Mechanism of action

Bacitracin interferes with the dephosphorylation of the C55-isoprenyl pyrophosphate, a molecule which carries the building blocks of the peptidoglycan bacterial cell wall outside of the inner membrane .

Clinical use

As bacitracin zinc salt, and in combination with other topical antibiotics (usually polymyxin B and neomycin), it is used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections. This ointment is sold in the United States under the brand name Neosporin.

In infants, it is sometimes administered intramuscularly for the treatment of pneumonias. This formulation is sold under the brand name BaciimĀ®.

Read more at Wikipedia.org


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Bacitracin Zinc Ointment available in unit dose pouches
From Drug Store News, 3/15/99

Alpharma USPD and Xact-dose Inc. announce the availability of the seventh unit-dose product to emerge from their alliance, Bacitracin Zinc Ointment in 0.9-gm unit dose pouches. Marketed by the U.S. Pharmaceuticals Division of Alpharma Inc., Bacitracin Zinc Ointment will be available in 44-pouch boxes, and will compete in a bacitracin market of $7.8 million, which includes private-label sales.

For additional information, contact Harold D. Brown at (800) 638-9096.

COPYRIGHT 1999 Lebhar-Friedman, Inc.
COPYRIGHT 2000 Gale Group

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