Blue rubber bleb nevus
Blue rubber bleb nevus syndrome (or "BRBNS", or "blue rubber bleb syndrome, or "blue rubber-bleb nevus", or "Bean's syndrome") is a rare disorder that consists mainly of abnormal blood vessels affecting the gastrointestinal tract. more...
It causes several cavernous-type hemangiomas and has a potential for serious or fatal bleeding. Lesions are most commonly found in the small intestine and distal large bowel. The causes of this syndrome are unknown. Not more than a few hundred cases have been described worldwide.
It was first described by Gascoyen in 1860. In 1958 William Bennett Bean described the lesions further and came up with the term BRBNS, chosen because the 'cutaneous hemangiomas have the look and feel of rubber nipples'.
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