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Canine distemper

Canine distemper is a viral disease affecting animals in the families Canidae, Mustelidae, Mephitidae, Procyonidae, and possibly Felidae (though not domestic cats; feline distemper or panleukopenia is a similar, but different, virus exclusive to cats). more...

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Infection

Dogs from four months to four years old are particularly susceptible. It prevails most in spring and autumn. Canine distemper virus (CDV) spreads through the air and through contact with infected bodily fluids. The time between infection and disease is 14 to 18 days.

Canine distemper virus has a tropism for lymphoid, epithelial, and nervous tissues. Therefore, the typical pathologic features of canine distemper include lymphoid depletion (causing immunosuppression and leading to secondary infections), interstitial pneumonia, encephalitis with demyelination, and hyperkeratosis of foot pads . Histologic examination reveals intranuclear and intracytoplasmic eosinophilic inclusion bodies in numerous tissues.

Symptoms

  • Dullness and redness of the eye
  • Discharge from nose
  • Vomiting and diarrhea
  • Cough
  • Shivering
  • Fever
  • Loss of appetite and energy
  • Weight loss
  • Seizures
  • Thickened footpads

Diagnosis

The above symptoms, especially fever, respiratory signs, neurological signs, and thickened footpads found in unvaccinated dogs strongly indicate canine distemper. Finding the virus by various methods in the dog's conjunctival cells gives a definitive diagnosis.

Treatment and prevention

There is no specific treatment for canine distemper. The dog should be treated by a veterinarian, usually with antibiotics for secondary bacterial infections, intravenous fluids, and nutritional supplements. The prognosis is poor.

There exist a number of vaccines against canine distemper for dogs and domestic ferrets, which in many jurisdictions are mandatory for pets. The type of vaccine should be approved for the type of animal being inoculated, or else the animal could actually contract the disease from the vaccine. Animals should be quarantined if infected. The virus is destroyed in the environment by routine cleaning with disinfectants.

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Virus outbreak has experts worried for dogs 76 distemper cases since
From Chicago Sun-Times, 8/20/04 by Raksha Varma

Chicago has seen an outbreak of a distemper virus that can be deadly to dogs -- 76 cases reported in Chicago since April, while none were reported last year, the Department of Animal Care and Control said Thursday.

The virus is a 200-year-old killer said to be the leading cause of death in U.S.-born-and-bred pets up until the 1950s when specialized immunizations became available.

Officials don't know the cause of the outbreak but plan to meet next month to study it.

Humans and cats cannot contract the virus, which is fatal about 50 percent of the time in dogs, the department said. Pets that don't croak are usually prone to brain damage and other ailments, such as seizures, two-thirds of the time.

"Canine distemper is a serious threat," said Dr. John Lednicky, an assistant professor of pathology at Loyola University Chicago Stritch School of Medicine in Maywood. "Vaccinations help to keep your dog safe. But nothing is foolproof because the strains change so rapidly."

Canine distemper is an RNA virus that belongs to the same family responsible for measles in humans. Three different strains of the lethal disease swept through Chicago, Lednicky said, adding that outbreaks were present in 1998, 2000 and 2001.

Vaccinations, routinely administered in an annual veterinarian's physical, usually safeguard your pet against most strains.

Dogs that are not properly vaccinated contract the virus from the air, contact with other infected dogs in parks and exposure to wooded areas, the department said. Foxes, coyotes and raccoons, which inhabit wooded areas, are said to be the largest carriers of the disease.

There is no cure for the virus, which was first correctly described in the 18th century by Dr. Edward Jenner, remembered as the father of immunology and conqueror of smallpox, Lednicky said.

The virus was probably carried to Europe by Spaniards returning from an expedition to Peru.

Copyright The Chicago Sun-Times, Inc.
Provided by ProQuest Information and Learning Company. All rights Reserved.

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