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Cardiac arrest

A cardiac arrest is the cessation of normal circulation of the blood due to failure of the ventricles of the heart to contract effectively during systole. The resulting lack of blood supply results in cell death from oxygen starvation. Cerebral hypoxia, or lack of oxygen supply to the brain, causes victims to lose consciousness and stop breathing. more...

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Cardiac arrest is a medical emergency that, if left untreated, invariably leads to death within seconds to minutes. The primary first-aid treatment for cardiac arrest is cardiopulmonary resuscitation (commonly known as CPR).

Etiology

Coronary heart disease (commonly known as coronary artery disease, or CAD) is the predominant disease process associated with sudden cardiac death in the United States. The incidence of CAD in individuals who suffer sudden cardiac death is between 64 and 90%. Other causes of cardiac arrest include electrocution and near-drowning, as well as other cardiac conditions such as the cardiomyopathies.

In children, cardiac arrest is typically caused by hypoxia from other causes such as near-drowning. With prompt treatment survival rates are high.

Every fatal injury or illness ultimately terminates in cardiac arrest, which is a natural part of the processes of death.

Treatable causes

There are 8 reversible causes of cardiac arrest, known as the "4Hs and 4Ts". They are looked for and treated by ambulance technicians/paramedics or by medical staff at the hospital while undertaking advanced life support, protocols for which will be used alongside any specific treatments for each of the causes. Lay rescuers performing basic life support can generally neither identify or treat them (with the exception of hypovolemia due to external bleeding), and so can offer only supportive treatment pending the arrival of emergency medical services.

4 Hs:-

  • Hypoxia - A lack of oxygen to the brain and other vital organs. This is treated by providing the patient with oxygen, either through a bag-valve-mask device, or by inserting an endotracheal tube (intubation)
  • Hypovolemia - A lack of circulating body fluids, principally blood. This is usually (though not exclusively) caused by some form of bleeding. Peri-arrest treatment includes giving IV Fluids and blood transfusions, and controlling the source of any bleeding - direct pressure for external bleeding, or emergency surgery (usually an immediate emergency thoracotamy on the ward, to clamp off the descending aorta and achieve haemostasis, the bleed is then repaired properly once the patient has regained circulation) for internal bleeding
  • Hypo/Hyper-metabolic disorders - An abnormally high or low level of electrolytes such as potassium and calcium circulating the body. An arterial blood gas and blood electrolyte test are performed to find the problem, then IV crystalloids are given to correct it.
  • Hypothermia - A low core body temperature, defined clinically as a temperature of less than 35 degrees celsius. The patient is re-warmed either by using a cardiac bypass or by irrigation of the body cavities (such as thorax, peritoneum, bladder) with warm fluids; or warmed IV fluids. CPR only is given until the core body temperature reached 30 degrees celsius, as defibrillation is ineffective at lower temperatures. Patients have been known to be successfully resuscitated after periods of hours in hypothermia and cardiac arrest, and this has given rise to the often quoted medical truism "You're not dead until you're warm and dead"


4 Ts:-

Read more at Wikipedia.org


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Resuscitative hypothermia after cardiac arrest: performance in a community hospital
From CHEST, 10/1/05 by Cindy Grimes

PURPOSE: Induced hypothermia improves outcome after cardiac arrest due to ventricular fibrillation. We studied induced hypothermia in a community hospital setting after cardiac arrest due to any cause.

METHODS: A case-control study was conducted in a publicly owned, non-academic, acute care hospital. Thirty-eight patients who underwent induced hypothermia were compared to 103 patients who did not undergo hypothermia. After resuscitation from cardiac arrest, patients underwent hypothermia using an established protocol at the discretion of the treating clinicians. Hypothermia was achieved with either external devices or an intravascular cooling catheter system. Outcome measures included mortality, neurologic recovery, and length of stay (LOS).

RESULTS: The groups were similar in age, sex, APACHE III score, and Glasgow Coma Score (GCS). Hospital mortality in the hypothermia group was 53% versus 71% in the control group (p=0.07). Hospital mortality in 10 patients treated with intravascular cooling was 40%. Compared to Apache III predicted mortality, the hypothermia group mortality ratio was 0.76, versus 1.4 for the control group. Among survivors, the change in GCS from admission to ICU discharge was 7.2 +/- 4.0 (baseline 4.4, discharge 11.7) in the hypothermia group and 6.6 +/- 4.3 (baseline 4.0, discharge 10.6) in the control group (p=0.32). Also among survivors, the ICU LOS was 2.6 +/- 3.5 days less than Apache III predicted in the hypothermia group versus 0.5 +/- 6.8 days less in the control group (p=0.08).

CONCLUSION: Induced hypothermia following cardiac arrest performs well in a community hospital setting. The intravascular cooling catheter was a safe, effective means of inducing hypothermia with a trend towards improved outcomes. Induced hypothermia may be applicable to all cardiac arrest patients regardless of cause.

CLINICAL IMPLICATIONS: Induced hypothermia is safe, simple, and inexpensive. Hospital protocols may help to ensure timely application of this important intervention. Intravascular cooling techniques show promise in terms of ease of use, effectiveness of cooling, and maintaining accessibility to the patient. Further study is needed to determine the optimal patients and techniques for therapeutic hypothermia.

DISCLOSURE: Kenneth Hurwitz, None.

Cindy Grimes RN Rhonda Anderson MSN Todd Horiuchi MD Mauricio Concha MD Bruce Fleegler MD Kenneth Hurwitz MD * Sarasota Memorial Hospital, Sarasota, FL

COPYRIGHT 2005 American College of Chest Physicians
COPYRIGHT 2005 Gale Group

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