Citalopram chemical structure
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Celexa

Citalopram or nitalapram is an antidepressant drug used to treat depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety. more...

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Citalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is sold under the brand-names Celexa™ (U.S., Forest Laboratories, Inc.), Cipramil™ (Europe and Australia) and Talohexane (Australia).

Citalopram was originally created by the pharmaceutical company Lundbeck although the patent for it expired in 2003, allowing other companies to legally produce generic versions.

Lundbeck has recently released a new SSRI drug called escitalopram oxalate (also known as Cipralex or Lexapro) derived from the citalopram molecule.

Reported side effects

Over 10% of patients

  • Feeling sick or tired
  • Drowsiness
  • Dry mouth
  • Sweating
  • Trembling
  • Headache
  • Dizziness
  • Difficulty sleeping
  • Feeling agitated or nervous
  • Constipation or diarrhoea
  • Blurred vision
  • Missed heartbeats
  • Feeling of weakness
  • Difficulty ejaculating

Over 1% of patients

  • Itchiness
  • Rashes
  • Migraine
  • Strange dreams
  • Changes in taste
  • Decreased libido or impotence
  • Failure to orgasm
  • Painful menstruation
  • Tingling in fingers or toes
  • Loss of memory or concentration
  • Changes in appetite (increase or lack of)
  • Mood changes
  • Anxiety
  • Confusion
  • Yawning
  • Indigestion
  • Vomiting
  • Stomach ache
  • Flatulence
  • Increased saliva
  • Change in weight
  • Dizziness on standing up
  • Fast heartbeat
  • Changes in blood pressure
  • Runny nose
  • Sinusitis
  • Changes in passing urine

Rare (under 1% of patients)

  • Muscle pain
  • Convulsions
  • Increased libido
  • Coughing
  • Abnormal movement of the face or body
  • Ringing in the ears
  • Mood changes
  • Slowing of the heartbeat
  • Photosensitivity
  • Allergic reactions
  • Fainting
  • Suicidal ideation

Other side effects

Occasionally, panic attacks, thoughts of suicide or self-harm may occur or increase in the first few weeks, before the antidepressant effect starts.

Other occasional effects include leaking of milk from the breasts, changes in heart rhythm, swelling of the skin, joint pain or severe allergic reactions.

Overdose

Citalopram is considered relatively safe in overdose; although coma at a dosage of 400mg has been observed. It is important to seek medical attention if an overdose of this medication has occurred.

Read more at Wikipedia.org


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Just what the doctor ordered—or is it? - similarity of brand names of Celebrex, Celexa and Cerebyx lead to pharmacy errors - Brief Article
From Running & FitNews, 10/1/00

Pharmacists might make a mistake when filling your prescription for Celebrex, the new COX-2 inhibitor, anti-inflammatory medication used mainly for arthritis pain (see Running & FitNews, March 1999). Within just a few weeks of hitting the market, at least 40 documented errors were reported to the Institute for Safe Medication Practices, a non-profit, educational and watch dog organization for the pharmaceutical industry Confusion has occurred due to the similarity among three different medications: Celebrex, Celexa (an antidepressant), and Cerebyx (an anti-seizure medication). Since that original report many more mistakes have occurred.

The potential for fatal errors involving an overdose of selective serotonin re-uptake inhibitors (SSRIs) is tremendous because of the popularity of both types of drugs. Most major antidepressants currently in use are of the SSRI type including Paxil, Zoloft, Prozac, and Celexa and account for millions of prescriptions. If a patient is currently taking an SSRI and Celexa is dispensed by mistake when Celebrex was intended, a potentially fatal overdose could occur. The Institute for Safe Medication Practices is requesting that the manufacturer and the Food and Drug Administration consider renaming Celebrex in order to avoid confusion. Meanwhile, if you are prescribed Celebrex for a sports injury or chronic arthritis, make certain every time you fill your prescription that you are getting what the doctor ordered. (For more information, contact the Institute for Safe Medication Practices, 301-497-2375 or wwwismp.org)

COPYRIGHT 2000 American Running & Fitness Association
COPYRIGHT 2003 Gale Group

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