Find information on thousands of medical conditions and prescription drugs.

Craniodiaphyseal dysplasia

Craniodiaphyseal dysplasia (also known as CDD or lionitis) is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy. The calcium deposits decrease the size of cranial foramina, and can also decrease the hole in the cervical spinal canal. In the few cases recorded, most of the sufferers died in childhood. Among the medical signs are dacryocystitis, seizures, mental retardation, and paralysis, each of which is a complication resulting from the diminutive foramina. more...

Home
Diseases
A
B
C
Angioedema
C syndrome
Cacophobia
Café au lait spot
Calcinosis cutis
Calculi
Campylobacter
Canavan leukodystrophy
Cancer
Candidiasis
Canga's bead symptom
Canine distemper
Carcinoid syndrome
Carcinoma, squamous cell
Carcinophobia
Cardiac arrest
Cardiofaciocutaneous...
Cardiomyopathy
Cardiophobia
Cardiospasm
Carnitine transporter...
Carnitine-acylcarnitine...
Caroli disease
Carotenemia
Carpal tunnel syndrome
Carpenter syndrome
Cartilage-hair hypoplasia
Castleman's disease
Cat-scratch disease
CATCH 22 syndrome
Causalgia
Cayler syndrome
CCHS
CDG syndrome
CDG syndrome type 1A
Celiac sprue
Cenani Lenz syndactylism
Ceramidase deficiency
Cerebellar ataxia
Cerebellar hypoplasia
Cerebral amyloid angiopathy
Cerebral aneurysm
Cerebral cavernous...
Cerebral gigantism
Cerebral palsy
Cerebral thrombosis
Ceroid lipofuscinois,...
Cervical cancer
Chagas disease
Chalazion
Chancroid
Charcot disease
Charcot-Marie-Tooth disease
CHARGE Association
Chediak-Higashi syndrome
Chemodectoma
Cherubism
Chickenpox
Chikungunya
Childhood disintegrative...
Chionophobia
Chlamydia
Chlamydia trachomatis
Cholangiocarcinoma
Cholecystitis
Cholelithiasis
Cholera
Cholestasis
Cholesterol pneumonia
Chondrocalcinosis
Chondrodystrophy
Chondromalacia
Chondrosarcoma
Chorea (disease)
Chorea acanthocytosis
Choriocarcinoma
Chorioretinitis
Choroid plexus cyst
Christmas disease
Chromhidrosis
Chromophobia
Chromosome 15q, partial...
Chromosome 15q, trisomy
Chromosome 22,...
Chronic fatigue immune...
Chronic fatigue syndrome
Chronic granulomatous...
Chronic lymphocytic leukemia
Chronic myelogenous leukemia
Chronic obstructive...
Chronic renal failure
Churg-Strauss syndrome
Ciguatera fish poisoning
Cinchonism
Citrullinemia
Cleft lip
Cleft palate
Climacophobia
Clinophobia
Cloacal exstrophy
Clubfoot
Cluster headache
Coccidioidomycosis
Cockayne's syndrome
Coffin-Lowry syndrome
Colitis
Color blindness
Colorado tick fever
Combined hyperlipidemia,...
Common cold
Common variable...
Compartment syndrome
Conductive hearing loss
Condyloma
Condyloma acuminatum
Cone dystrophy
Congenital adrenal...
Congenital afibrinogenemia
Congenital diaphragmatic...
Congenital erythropoietic...
Congenital facial diplegia
Congenital hypothyroidism
Congenital ichthyosis
Congenital syphilis
Congenital toxoplasmosis
Congestive heart disease
Conjunctivitis
Conn's syndrome
Constitutional growth delay
Conversion disorder
Coprophobia
Coproporhyria
Cor pulmonale
Cor triatriatum
Cornelia de Lange syndrome
Coronary heart disease
Cortical dysplasia
Corticobasal degeneration
Costello syndrome
Costochondritis
Cowpox
Craniodiaphyseal dysplasia
Craniofacial dysostosis
Craniostenosis
Craniosynostosis
CREST syndrome
Cretinism
Creutzfeldt-Jakob disease
Cri du chat
Cri du chat
Crohn's disease
Croup
Crouzon syndrome
Crouzonodermoskeletal...
Crow-Fukase syndrome
Cryoglobulinemia
Cryophobia
Cryptococcosis
Crystallophobia
Cushing's syndrome
Cutaneous larva migrans
Cutis verticis gyrata
Cyclic neutropenia
Cyclic vomiting syndrome
Cystic fibrosis
Cystinosis
Cystinuria
Cytomegalovirus
Dilated cardiomyopathy
Hypertrophic cardiomyopathy
Restrictive cardiomyopathy
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Medicines

Peter Bogdanovich's 1985 film Mask drew public attention to the case of Roy L. "Rocky" Dennis, an American boy who died of the disorder in 1980.

Read more at Wikipedia.org


[List your site here Free!]


Movie characters show us the pain of being different
From Spokesman Review, The (Spokane), 7/5/02 by Dan Webster

Life can be hard for those who don't fit into some sort of mainstream category. From Holden Caulfield to Babe the pig, walking anomalies in physical, mental or emotional form tend not to get invited to the prom -- if you know what I mean.

Take "A Beautiful Mind" (2001, VHS/DVD) for example (not the real story, but the Ron Howard movie version of it). In emotional terms, John Nash is as different from his fellow colleagues, not to mention his students, as, say, John Merrick is to virtually anyone else physically.

Merrick, you'll recall, was the real person whose story David Lynch told in "The Elephant Man" (1980, VHS/DVD). As Merrick, John Hurt -- under several pounds of makeup -- was superb in showing that even a disfiguring disease such as multiple neurofibromatosis doesn't mean that a real, live person isn't living inside.

Nash and Merrick were based on real people. Hal Larson is pure fiction. Yet the issues raised by the movie about him, "Shallow Hal" (available for home viewing this week; see capsule review below), are again tied to the pain of being different.

And Hal is hardly the only one. Take the following characters:

* "Mask" (1985, VHS/DVD): In the trailers for this Peter Bogdanovich film, the teenage protagonist, Rocky Dennis (Eric Stoltz), is not seen. And there's a reason: Bogdanovich wanted Rocky's appearance, a dramatic facial distortion caused by the disease craniodiaphyseal dysplasia, to be as shocking as possible.

* "What's Eating Gilbert Grape" (1993, VHS/DVD): Johnny Depp plays the title character, and Leonardo DiCaprio gives the best performance, but the film's plot (by Peter Hedges based on his novel) revolves around Momma Grape, a woman who is so overweight that she can't even move from the couch.

* "Edward Scissorhands" (1990, VHS/DVD): Depp again, here in the role that broke him out of his "21 Jump Street" television persona. Tim Burton ("Pee-wee's Big Adventure," "Batman") continued his study of characters who, for some reason, don't fit into the mainstream. The problem: Edward literally has scissors for hands.

* "Benny & Joon" (1993, VHS/DVD): Joon (Mary Stuart Masterson), a young woman whose mental illness leads her to set fires, is romanced by a guy named Sam (Depp, yet again). Sam has his own problems; he acts as if he's the second coming of Charlie Chaplin. When they fall in love, real-life problems threaten to intrude. Special note: "Benny & Joon" was filmed in Spokane.

* "Cyrano de Bergerac" (1990, VHS only): Gerard Depardieu is the latest actor to play this big-nosed cavalier, a list that includes everyone from Jose Ferrer (who won an Oscar for Michael Gordon's 1950 version of the Edmond Rostand play, available on VHS and DVD) to Steve Martin ("Roxanne," 1987, VHS/DVD). But no one is better than Depardieu as a man with a poet's soul, a warrior's temperament and a nose the size and shape of a banana.

"Frankenstein" (1930, VHS/DVD): Lurking somewhere between Edward Scissorhands and John Merrick, Henry Frankenstein's monster (poignantly played by Boris Karloff) is afraid of fire, lonely to the point of psychosis and open to friendship to those not put off by his hideous appearance.

In all these cases, the problem is not with the characters as much as it is with a society not programmed to accept anyone with vastly different attitudes or physical form.

Some of the movies, "Benny & Joon" in particular, settle for the easy answer (love will solve all your problems). Others, though, show that everyone wants pretty much the same thing out of life. Rocky Dennis from "Mask" wants a girlfriend. Edward Scissorhands simply wants to fit in. Cyrano de Bergerac wants to believe that love makes life a noble venture.

All of them have this in common: They understand completely Frankenstein's monster when he utters his most memorable and heartbreaking plea: "Friend!"

The week's major release on home video:

Shallow Hal

***

Hal (Jack Black) was messed up by his father. His particular neurosis is that he consistently tries to date beautiful women, who just as consistently reject him. Until one day, caught in an elevator with self-help guru Tony Robbins, he is programmed to see only the inner beauty in everyone.

That's how he sees Rosemary (Gwyneth Paltrow), who to Hal looks like -- well, Gwyneth Paltrow, though to the rest of the world Rosemary looks like three Gwyneths packed into one. No matter, Hal falls in love. But what happens when his vision clears?

As one astute critic pointed out, "Shallow Hal" isn't about how hard life is when you don't fit into a "normal" physical category, it's about how hard it is to be the boyfriend of someone who is the perpetual butt of jokes. That bit of self-absorption aside, the movie works because it makes Hal and his friend Mauricio (Jason Alexander) the butt of jokes, too. (Alexander does mostly a variation on his "Seinfeld" character George.)

It also works because of Black, who is such an oddity: an on-the- edge actor who can still play-act the sensitive guy. Finally, don't forget Paltrow, who has the uncanny ability to be beautiful and yet convince us that she's not. (VHS, DVD) Rated PG-13 (language and sexual content).

Copyright 2002 Cowles Publishing Company
Provided by ProQuest Information and Learning Company. All rights Reserved.

Return to Craniodiaphyseal dysplasia
Home Contact Resources Exchange Links ebay