The structure of Diethylcarbamazine
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Diethylcarbamazine

Diethylcarbamazine (DEC) (C10H21N3O) is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. DEC is indicated for treatment of individual patients with certain filarial diseases. These diseases include: lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori; tropical pulmonary eosinophilia; and loiasis. more...

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DEC continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.

Trade names

  • Carbilazine
  • Caricide
  • Cypip
  • Ethodryl
  • Notézine
  • Spatonin

Read more at Wikipedia.org


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Gale Encyclopedia of Medicine : Elephantiasis $5.99 Preventative chemotherapy of canine dirofilariasis with diethylcarbamazine (SAM-TR-68-95)
Nature and control of side-reactions due to diethylcarbamazine in the treatment of Malayan filariasis

Role Of Diethylcarbamazine In Patients Of Bronchial Asthma - A Clinical Study - DEC - Abstract
Purpose: Leucotrienes have a role in pathogenesis of Bronchial asthma (BA). Modulation of production or action of leucotrienes can have therapeutic implication. DEC is known to inhibit formation of
Cost of mass annual single dose diethylcarbamazine distribution for the large scale control of lymphatic filariasis
Economic analysis of the revised strategy to control lymphatic filariasis with mass annual single dose diethylcarbamazine (DEC) at 6 mg/kg body weight ...
Long-term effect of diethylcarbamazine citrate of microfilareamia status in treated individuals
Follow up of microfilaraemic individuals infected with Wuchereria bancrofit at five years after treatment was carried out in a tea workers population.
Endosymbiotic Wolbachia of parasitic filarial nematodes as drug targets
The parasitic nematodes Wuchereria bancrofti, Brugia malayi and B. timori cause a dreadful disease in humans known as lymphatic filariasis, which afflicts ...
Making the best of what we have: a plea for wider use of anthelmintics
Over the last 15 yr, the World Health Assembly has passed several resolutions calling for the control, elimination or even eradication of diseases caused ...
Attack on elephantiasis. Antibiotic offers weapon against tropical scourge
Of all the exotic diseases that afflict people, elephantiasis ranks among the most dreaded. The threadlike, parasitic worm that causes this lethal disease ...
A survey of bancroftian filariasis for microfilariae & circulating antigenaemia in two villages of Madhya Pradesh
Background & objectives: The estimation of filariasis prevalence in Panna district of Madhya Pradesh was so far relied upon clinical and night blood smear ...
Histopathologic improvement with lymphedema management, Leogane, Haiti
In countries where bancroftian filariasis is endemic, lymphedema of the leg is a public health problem, particularly for women, who are disproportionately ...

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