You routinely administer combination drugs.. but do you know what's in them? To find out, match each combination of ingredients in Section II with its correct name in Section I.
SECTION I
1. Lonox (Geneva)
2. Dyazide (GlaxoSmithKline)
3. Opcon-A (Bausch & Lomb)
4. Sinemet CR (DuPont)
5. Aquatab DM (Adams)
SECTION II
a. naphazoline HCI, 0.027%; pheniramine maleate, 0.315%
These eyedrops contain naphazoline, an ocular decongestant that constricts blood vessels to eliminate redness, and pheniramine, an antihistamine, to relieve itching. Tell your patient to avoid touching the dropper tip to her eyes or fingers to prevent contamination.
b. hydrochlorothiazide, 25 mg; triamterene, 37.5 mg
Used to treat hypertension, this combination contains hydrochlorothiazide, a thiazide diuretic, and triamterene, a potassium-sparing diuretic. It could cause a mild photosensitivity reaction, so tell your patient to apply sunscreen to exposed skin if he goes outdoors.
c. guaifenesin, 1200 mg; dextromethorphan HBr, 60 mg
This tablet relieves cough and helps thin bronchial mucus. Guaifenesin is an expectorant and dextromethorphan is a nonopioid cough suppressant. Advise your patient to take the medication with a full glass of water to enhance the effect of guaifenesin.
d. levodopa, 100 mg, 200 mg; carbidopa, 25 mg, 50 mg
This extended-release tablet is prescribed to treat Parkinson disease. Levodopa reduces tremors and other Parkinson symptoms after it converts into dopamine in the brain. Carbidopa inhibits levodopa metabolism, enabling more of it to pass into the brain. Tell your patient that taking this drug may cause his urine to darken.
e. diphenoxylate HCI, 2.5 mg; atropine sulfate, 0.025 mg
Used to relieve diarrhea, this combination contains diphenoxylate, an opioid derivative that slows motility, and atropine, an anticholinergic that relieves smooth-- muscle spasms. Tell your patient to suck on sugar-free hard candy if her mouth feels dry.
ANSWERS: 1e, 2b, 3a, 4d, 5c
Marcy Portnoff Gever, RPh, MEd, author of Drug Challenge, is an independent pharmacist consultant and educator in Voorhees, N.J.
Copyright Springhouse Corporation Jun 2001
Provided by ProQuest Information and Learning Company. All rights Reserved
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