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Dupuytren's contracture

Dupuytren's contracture is a fixed flexion contracture of the hand where the fingers bend towards the palm and cannot be fully extended (straightened). It is named after the famous surgeon Baron Guillaume Dupuytren, who described an operation to correct the affliction. more...

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The ring finger and pinky finger are the fingers most commonly affected, but Dupuytren's contracture may affect any or all of the fingers. Dupuytren's contracture progresses slowly and is usually painless. In patients with this condition, the tissues under the skin on the palm of the hand thicken and shorten so that the tendons connected to the fingers cannot move freely. The palmar fascia becomes hyperplastic and undergoes contracture. As a result, the affected fingers start to bend more and more and cannot be straightened.

Incidence increases after the age of 40; at this age men are affected more often than women. After the age of 80 the distribution is about even.

Risk Factors

Regular operation of heavy machinery increases one's risk of developing Dupuytren's contracture; family history, diabetes, liver disease, alcoholism, epilepsy and pulmonary tuberculosis are also factors. Surgery of the hand may trigger growth of Dupuytren nodules and cords if an inclination existed before. Dupuytren's contracture may accompany fibrosing syndromes such as Peyronie's disease, Ledderhose's disease and Riedel's struma.


  • Surgery (in cases of severe contracture)
  • Radiation therapy (specifically in early stages)
  • Needle aponevrotomy (removes the contracture)
  • Triamcinolone injections provide some relief

Surgical management consists of opening the skin over the affected cords of fibrous tissue, and dissecting the fascia away. The tendons can then be brought out to length. The procedure is not curative, and patients may need re-do surgery, however, the thickened fascia often invests the digital nerves and arteries, so there is significant risk of de-vascularization of the digit.

Treatment of Dupuytren's disease with low energy x-rays (radiotherapy) may cure Morbus Dupuytren on a long term, specifically if applied in early stages of the disease. Needle aponevrotomy is a minimal invasive technique where the cords are weakened through the insertion and manipulation of a small needle. Once weakened, the offending cords may be snapped by simply pulling the finger(s) straight. The nodules are not removed and might start growing again. Currently in phase III of FDA approval is another promising therapy, the injection of collagenase. This procedure is similar to needle aponevrotomy, however the chords are weakened through the injection of small amounts of an enzyme that dissolves them.


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Dermofasciectomy in the management of Dupuytren's disease
From Journal of Bone and Joint Surgery, 1/1/00 by Armstrong, J R

Dupuytren's disease may present with well-defined subcutaneous cords or as more diffuse disease

with involvement of the skin. Fasciectomy is the procedure commonly carried out for the full range of disease, but is associated with rates of recurrence of up to 66%. We reviewed 143 rays in 103 patients undergoing dermofasciectomy for diffuse disease with involvement of the skin. We found recurrence in 12 rays (8.4% of rays; 11.6% of patients) during a mean follow-up of 5.8 years, eight as cords and four as nodules. We suggest that dermofasciectomy is a better method of disease control than fasciectomy for the more diffuse type of disease with involvement of the skin.

Received 15 January 1999; Accepted after revision 21 April 1999

Dupuytren's disease on the ulnar side of the hand varies from a relatively benign, slowly contracting, well-localised pretendinous cord of the ray of the ring finger, with slowly progressive flexion contracture of the metacarpophalangeal joint, to a much more aggressive, relatively diffuse disease with involvement of the skin of the little finger ray and flexion contracture of the metacarpophalangeal and proximal interphalangeal joints.

Many surgeons perform fasciectomy for the whole spectrum of Dupuytren's disease. The outcome is clearly unsatisfactory with rates of recurrence ranging from 27% to 66%.1-8 Hueston7 recorded recurrence in 28% after fastciectomy, but called the appearance of an abductor band in the little finger9 after excision of a pretendinous cord extension rather than recurrence; he also noted that most recurrences after fasciectomy were in the little finger ray. About half of the recorded recurrences required further operation which we consider to be a reflection, in part, of a reluctance towards surgery by both surgeon and patient.

Segmental aponeurectomy has been promoted as a procedure with a much lower rate of complications than fasciectomy, but recurrence was 36% when determined non-selectively for all cases.10 Preoperative skeletal traction to extend a flexed digit before fasciectomy is 'commonly' associated with recurrence. 11

It is not our practice to use a single procedure for all patients with Dupuytren's disease but to match the surgical intervention to the nature of the disease. Benign pretendinous disease of the ring finger can be treated adequately by proximal and distal palmar se mental aponeurectomy. We carry out limited fasciectomy R when well-localised cords have resulted in flexion contracture of the proximal interphalangeal joint. When the disease appears to be more diffuse and involvement of the skin is marked we resort to dermofasciectomy.13 Contrary to Hueston's view 13 that replacement of the skin is the allimportant factor in the control of the disease, we believe that dermofasciectomy should be thought of as a subtotal preaxial amputation of the digit, removing, all tissue which may result in further flexion contracture.14

We have reviewed the effectiveness of dermofasciectomy for relatively diffuse Dupuytren's disease with involvement of the skin.

Patients and Methods

Between 1986 and 1995 we carried out dermofasciectomy in 135 patients.

Of these, 103 with a total of 143 dermofasciectomies were available for review; five patients had died and 27 had been lost to follow-up. There were 82 men and 21 women with a mean age at the time of operation of 69.2 years (37.3 to 87.6). Of the 143 dermofasciectomies, 110 had been performed as a primary procedure and 33 for recurrent disease. Table I gives the number of previous fasciectomies carried out on the ray undergoing dermofasciectomy for recurrent disease. Our aim was to determine whether there was recurrence of Dupuytren's disease in the operated ray and, if so, whether it was in the form of a nodule or a cord. The number of previous operations for Dupuytren's disease carried out on the operated ray was recorded.

Operative technique. The skin was prepared and draped in a standard fashion, with the limb elevated and an arm tourniquet inflated to 250 mmHg to prevent blood from obscuring the surgical field. Our standard dermofasciectomy involved excision of skin from the distal palmar crease to the distal flexion crease of the interphalangeal joint carried out to the midaxial line on either side of the digit (Fig. 1). The neurovascular bundles were identified in the proximal end of the wound and exposed distally. The pretendinous and subcutaneous tissue between them was then excised. Next, the ulnar element was dealt with. In the little finger this is usually extensive when the disease has resulted in proximal interphalangeal flexion, and its excision exposes the insertion of abductor digiti minimi on to the proximal phalanx, the ulnar side of the periosteum of the proximal phalanx, the ulnar side of the capsule of the proximal interphalangeal joint and the ulnar side of the border of the extensor mechanism. The dorsal branch of the ulnar nerve must be protected (Fig. 2). The radial element was less constant and, when present, was excised (Fig. 3). In doing so the dorsal branch of the radial digital nerve should be protected. The amount of correction of the contracture was probably similar to that achieved by a limited fasciectomy. The tourniquet was then released. To close the resultant defect a full-thickness skin graft was used. For a little finger, this was usually about 6 cm long, 3.5 cm wide proximally and 2.5 cm wide distally. It was taken from the hairless area of the proximal, volar forearm or from the medial aspect of the arm as a long ellipse, and the donor site was closed by direct suture. After removal of the fat from its deep surface with scissors the graft was accurately sutured into the defect (Fig. 4). Additionally, some four sutures were placed along each side of the graft and left long to be loosely tied over a bulky gauze dressing. This stabilises the graft on the finger and helps to prevent shearing of vessel ingrowth and significant finger flexion. A full 'boxing-glove' dressing was then lightly applied in order to protect the hand for one week. The hand and forearm were elevated in a sling. After confirmation of successful adherence of the skin graft (Fig. 5) gentle mobilisation was started after removal of the dressing. More aggressive mobilisation began at two weeks as the graft stabilised.


The mean follow-up was 5.8 years (2.1 to 11.5). The distribution of rays undergoing dermofasciectomy is shown in Table 11. There were nine certain and three possible recurrences. The diagnosis of recurrence is clinical and often difficult; all doubtful recurrences were included. No patient had more than one recurrence, giving a rate of recurrence per ray of 8.4% and per patient of 11.6%. Eight of the recurrences were classified as cords (Fig. 6) and four as nodules (Fig. 7). Only one cord had progressed to recontracture.


Dermofasciectomy for Dupuytren's disease, although promoted by Hueston,12 has never been popular possibly because of over-cautious expectation of the 'take' of the skin graft on bared flexor sheaths and neurovascular bundles. It is our experience that a successful skin graft is to be expected unless both digital arteries have been damaged. 15-17 The robustness of the harvested skin has also been questioned. We found that forearm and arm donor sites gave good digital cosmesis and that the skin was sufficiently robust for most patients; both cosmesis and robustness can be improved by the use of submalleolar skin.14

The involved skin must be excised.18 The surgical technique which we used gave an excellent view of the underlying diseased tissues, which were usually seen to be more extensive after surgical exposure than had been observed on clinical examination. Wide excision of the preaxial tissues could be carried out without concern for vascularity of the overlying flap. Full-thickness skin grafts controlled bleeding and closed the resultant defect without longitudinal palmar scars or tension. The supple graft allowed excellent recovery of flexion. 17

Our results confirmed the low rates of recurrence of Dupuytren's disease after dermofasciectomy reported by others. 13,15,19-21 While enouraging reports of new methods such as the use of injected collagenase, are beginning to emerge, and while others are examining profiles of growth factors in active Dupuytren's disease as therapeutic targets,23 dermofasciectomy currently seems to be the best surgical technique for controlling diffuse Dupuytren's disease with involvement of the skin.

No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.


1. Tubiana R, Leclercq C. Recurrent Dupuytren's disease. In: Hueston JT, Tubiana R, eds. Dupuytren's disease. 2nd ed. Edinburgh: Churchill Livingstone, 1985:200-3.

2. Hakstian RW. Long term results of extensive fasciectomy. Br J Plast Surg 1966;19:140-9.

3. Tonkin MA, Burke FD, Varian JPW. Dupuytren's contracture: a comparative study of fasciectomy and dermofasciectomy in one hundred patients. J Hand Surg 1984;90-B: 156-62.

4. Foucher G, Cornil C, Lenoble E. Open palm technique for Dupuytren's disease: a five year follow-up. Ann Chir Main Memb Super 1992;11:362-6.

5. Adam RF, Loynes RD. Prognosis in Dupuytren's disease. J Hand Surg Am 1992; 17:312-7.

6. Cools H, Verstreken J. The open palm technique in the treatment of Dupuytren's disease. Acta Orthop BeIg 1994;60:413-20.

7. Hueston JT. Recurrent Dupuytren's contracture. Plast Recon Surg 1963;31;66-9.

8. Makela EA, jaroma H, Harju A, Anttila S, Vainio J. Dupuytren's contracture: the long tenn results after day surgery. J Hand Surg Br 1991;16:272-4.

9. Barton NJ. Dupuytren's disease arising from the abductor digiti mimi. J Hand Surg Br 1984;9:265-70.

10. Moermans JP. Segmental aponeurectomy in Dupuytren's disease. J Hand Surg Br 1991; 16:243-54.

11. Citron N, Messina JC. The use of skeletal traction in the treatment of severe primary Dupuytren's disease. J Bone Joint Surg [Br] 1998; 80-13:126-9.

12. Hueston JT. Limited fasciectomy for Dupuytren's contracture. Plast Recon Surg 1961;27:569-85.

13. Hueston JT. The control of recurrent Dupuytren's contracture by skin replacement. Brit J Plast Surg 1969;22:152-6.

14. Searle AE, Logan AM. A mid term review of the results of dermofasciectomy for Dupuytren's disease. Ann Chir Main Memb Super 1992;11:375-80.

15. Brotherston TM, Balakrishan C, Milner RH, Brown HG. Long term follow-up of dermofasciectomy for Dupuytren's contracture. Br J Plast Surg 1994;47:440-3.

16. Hall PN, Fitzgerald A, Sterne GD, Logan AM. Skin replacement in Dupuytren's disease. J Hand Surg Br 1997;22:193-7.

17. Logan AM, Brown HG, Lewis-Smith P. Radical digital dermofasciectomy in Dupuytren's disease. J Hand Surg Br 1985;10:353-7. 18. McCann BG, Logan A, Belcher H, Warn A, Warn RM. The

presence of myofibroblasts in the dermis of patients with Dupuytren's contracture: a possible source for recurrence. J Hand Surg Br 1993; 18:656-61.

19. Kelly C, Varian J. Dermofasciectomy: a long term review. Ann Chir Main Memb Super 1992;11:381-2.

20. Ketchum LD, Hixson FP. Dermofasciectorny and full thickness grafts in the treatment of Dupuytren's contracture. J Hand Surg Am 1987;12:659-64.

21. Ebelin M, Leviet D, Auclair E, Lemerle JP, Vilain R. The treatment of recurrent Dupuytren's disease by scalar incision and firebreak graft. Ann Chir Plast Esther 1991;36:26-30.

22. Badalamente NU, Hurst LC. Enzyme injection as a nonoperative treatment for Dupuytren's disease. Procs 7tb Congress of IFFSH, 1998.

23. Lappi DA, Martineau D, Maher PA, et al. Basic fibroblast growth factor in cells derived from Dupuytren's contracture: synthesis, presence and implications for treatment of the disease. J Hand Surg Am 1992;17:324-32.

J. R. Armstrong, FRCS, Senior Registrar in Plastic Surgery

J. S. Hurren, BSc, FRCS, Locum Consultant in Plastic Surgery

A. M. Logan, FRCS, Consultant Plastic Surgeon

Department of Plastic Surgery, West Norwich Hospital, Bowthorpe Road, Norwich NR2 3TU, UK.

Correspondence should be sent to Mr A. M. Logan.

Copyright British Editorial Society of Bone & Joint Surgery Jan 2000
Provided by ProQuest Information and Learning Company. All rights Reserved

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