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Erythroplakia

Erythroplakia is a flat red patch or lesion in the mouth that cannot be attributed to any other pathology. There are many other conditions that are similar in appearance and must be ruled out before a diagnosis of erythroplakia is made. Sometimes, a diagnosis is delayed for up to two weeks in order to see if the lesion spontaneously regresses on its own or if another cause can be found. Erythroplakia frequently is associated with dysplasia, and is thus a pre-cancerous lesion. more...

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Erythroplakia has an unknown cause but researchers presume it to be similar to the cause of squamous cell carcinoma. It is mostly found in elderly men around the ages of 65 - 74. It is commonly associated with smoking. The most common areas in the mouth where erythroplakia is found are the floor of the mouth, the tongue, and the soft palate. It appears as a red macule or plaque with well-demarcated borders. The texture is characterized as soft and velvety. An adjacent area of leukoplakia may be found along with the erythroplakia.

Microscopically, the tissue exhibits severe epithelial dysplasia, carcinoma-in-situ, or invasive squamous cell carcinoma in 90% of cases. There is an absence of keratin production and a reduced amount of epithelial cells. Since the underlying vascular structures are less hidden by tissue, erythroplakia appears red when viewed in a clinical setting.

Treatment involves biopsy of the lesion to identify extent of dysplasia. Complete excision of the lesion is sometimes advised depending on the histopathology found in the biopsy. Even in these cases, recurrence of the erythroplakia is common and, thus, long-term monitoring is needed.

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The role of non government organizations in cancer control programmes in developing countries
From Indian Journal of Palliative Care, 7/1/04 by Divya Parashar

Byline: Divya. Parashar

Health care in India is a three-tier system - the Government funded sector, the private sector, and Non Government Organizations (NGO). The Government funded health sector is the largest, providing care to two thirds of the population, but their facilities are usually overcrowded and they have limited resources. Private health facilities are commonly located in urban areas and provide care to the relatively affluent. NGOs provide standard health care at acceptable cost and have contributed significantly to bridging the wide gap between government and private sectors.

NGOs can play an important role in cancer control in any country and their activities should be complementary to governmental health care programmes, but unfortunately NGOs are not involved in National Cancer Control Plan (NCCP). Oncology facilities in most of the developing nations are either in overcrowded, under-resourced government funded institutes or within a private system that has western standards but is beyond what the common person can afford. NGOs can help bridge the gap in cancer care.

Jawaharlal Nehru Cancer Hospital and Research Centre at Bhopal is an NGO, run by a philanthropic organization with some help from the government. This organization in addition to providing treatment to cancer patients, has actively involved itself in prevention, screening, domiciliary care for terminally ill patients and research. It has screened around 18,500 patients for cancer through 115 free camps, since 1995 and identified 1820 patients with premalignant and malignant conditions. Biopsy was done on 55, FNAC on 280 and Pap smears on 400 patients. Since 1999 it has conducted around 60 cancer awareness campaigns covering all sections of society.

Tobacco Cessation Programmes were started in February, 2002. A team of 8 medical and para-medical people have been involved in disseminating knowledge on tobacco related health hazards to 10,273 persons - including school children - through documentary films, over head projectors, pamphlets, posters, booklets and informational stalls. People with leukoplakia, melanoplakia, erythroplakia or submucosal fibrosis were asked to attend Tobacco Cessation Clinic at hospital. So far, 400 people (367 males and 33 females) have registered in the Tobacco Cessation Clinic. Of the 400, 76 were smokers, 257 chewed tobacco, and 76 were both smokers and tobacco chewers. 10 persons quit tobacco use using meditation and 24 were put on the drug Bupriopion.

In 1996, the institute started a Palliative Care Unit. Domiciliary care started in 2000. Bereavement Services are also available.

NGOs should have an important role in cancer control in any country, because they can provide standard health care at an acceptable cost and can bridge the wide gap between the government and private sectors.

References

1. World Health Organization. Cancer Pain Relief and Pallative Care, WHO Techinical Report Series 804. Geneva: World Health Organization; 1990.

2. Herzler M, Franze T, Dietze F, Asadullah T (2000): Dealing with the issue 'care of the dying' in medical education: Result of a survey of 592 European physicians. Med Educ 2000;34:146-7.

3. Weissman DE, Abrahm JL. Education and Training In Palliative Care, in Principles and Practice of Palliative Care and Supportive Oncology 2nd Ed. Berger AM, Portenoy RK, Weissman DE, editor, Philadelphia: Lippincott Williams and Wilkins; 1998. p. 819-30.

4. Finlay IJ. House officers attitude towards terminal care. Med Educ 1986;20:507-51.

5. Sloan PA, Donnelly MB, Vanderveer B, et al. Cancer Pain education among family physicians. J Pain Symptom Manage 1997;14:74-81.

6. Field D, Bee Wee (2002). Preparation for Palliative care: Teaching about death, dying and bereavement in UK medical schools 2000-2001. Med Educ 2002;36:561-7.

7. Charlton R, Dovey S, Mizushima Y, Ford E. Attitudes to death and dying in the UK, New Zealand, and Japan. J Palliat Care 1995;1:42-7.

8. Williamson K, Von Gunten F, Garman K, Herbst L, Bluestein HG, Evans W. Improving knowledge in palliative medicine with a required hospice rotation for third year medical students. Acad Med 2004;79:777-82.

9. Liao S, Amin A, Rucker L. An innovative, longitudinal program to teach residents about end-of-life care. Acad Med 2004;79:752-7.

10. Weissman DE. Cancer Pain as a model for the training of physicians in palliative care In: Portenoy RK, Bruera E. Topics in Palliative Care Vol. 4, New York: Oxford University Press; 2003. p. 119-29.

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