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Estraderm

Estradiol (17-beta estradiol) is a sex hormone. Labelled the "female" hormone but also present in males it represents the major estrogen in humans. Critical for sexual functioning, estradiol also supports bone growth. more...

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Synthesis

Estradiol, like other sex steroids, is derived from cholesterol. After side chain cleavage and either utilizing the delta-5 pathway or the delta-4 pathway androstenedione is the key intermediary. Androstendione is either converted to testosterone which in turn undergoes aromatization to estradiol, or, alternatively, androstendione is aromatized to estrone which is converted to estradiol.

Conversion of testosterone to estradiol:

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Current Natural Hormone Replacement Therapy Prescription Options
From Townsend Letter for Doctors and Patients, 5/1/01 by Tori Hudson

The following medications are prescription products, made by pharmaceutical companies, of exclusively natural hormones; (plant derived and biochemically identical to endogenous hormones). These products often contain a filler, binder, or preservative that is not included in the same dosage and hormone preparation obtained from a compounding pharmacist. Contact your local compounding pharmacist, the International Academy of Compounding Pharmacists (900-927-4227; 713-933-8400) for a member pharmacist in your area, or one of the mail order compounding pharmacies-example/Women's International Pharmacy (1-800-279-5708). Ask for a doctor's packet from the Women's International Pharmacy.

Oral estrogens

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