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Gastric Dumping Syndrome

Gastric dumping syndrome, or rapid gastric emptying, happens when the lower end of the small intestine, the jejunum, fills too quickly with undigested food from the stomach. "Early" dumping begins during or right after a meal. Symptoms of early dumping include nausea, vomiting, bloating, cramping, diarrhea, dizziness and fatigue. "Late" dumping happens 1 to 3 hours after eating. Symptoms of late dumping include weakness, sweating, and dizziness. Many people have both types. more...

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In addition, people with this syndrome often suffer from low blood sugar, or hypoglycemia, because the rapid "dumping" of food triggers the pancreas to release excessive amounts of insulin into the bloodstream.

Causes

The main cause of dumping syndrome are patients of certain types of stomach surgery, such as a gastrectomy or gastric bypass surgery, that allow the stomach to empty rapidly. Patients with Zollinger-Ellison syndrome, a rare disorder involving extreme peptic ulcer disease and gastrin-secreting tumors in the pancreas, may also have dumping syndrome. Finally, patients with connective tissue conditions such as Ehlers-Danlos syndrome can experience "late" dumping as a result of decrease motility.

Diagnosis

Doctors diagnose dumping syndrome primarily on the basis of symptoms in patients who have had gastric surgery. Tests may be needed to exclude other conditions that have similar symptoms.

Treatment

Treatment includes changes in eating habits and medication. People who have gastric dumping syndrome need to eat several small meals a day that are low in carbohydrates and should drink liquids between meals, not with them. People with severe cases take medicine to slow their digestion. Doctors may also recommend surgery.


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Vagotomy
From Gale Encyclopedia of Medicine, 4/6/01 by Tish Davidson

Definition

Vagotomy is the surgical cutting of the vagus nerve to reduce acid secretion in the stomach.

Purpose

The vagus nerve splits into branches that go to different parts of the stomach. Stimulation from these branches causes the stomach to produce acid. Too much stomach acid leads to ulcers that may eventually bleed and create an emergency situation.

Vagotomy is performed when acid production in the stomach can not be reduced by other means. It is used when ulcers in the stomach and duodenum do not respond to medication and changes in diet. It is an appropriate surgery when there are ulcer complications, such as obstruction of digestive flow, bleeding, or perforation. The frequency with which elective vagotomy is performed has decreased in the past 20 years as drugs have become increasingly effective in treating ulcers. However, the number of vagotomies performed in emergency situations has remained about the same.

Vagotomy is often performed in conjunction with other gastrointestinal surgery, such as partial removal of the stomach (antrectomy or subtotal gastrectomy). There are several types of vagotomies. Truncal vagotomy severs the trunk of the vagus nerve as it enters the abdomen. Parietal cell or proximal gastric vagotomy leaves the trunk intact, but severs the branches that go to different parts of the stomach.

Precautions

Patients who receive vagotomies are most often seen in emergency situations where bleeding and perforated ulcers make it necessary to act immediately. As with any major surgery, people who use alcohol excessively, smoke, are obese, and are very young or very old are at higher risks for complications.

Description

Vagotomy is performed under general anesthesia by a surgeon in a hospital. The surgeon makes an incision in the abdomen and locates the vagus nerve. Either the trunk or the branches leading to the stomach are cut. Then the abdominal muscles are sewn back together, and the skin is closed with sutures.

Often, other gastrointestinal surgery is performed at the same time as the vagotomy. Part of the stomach may be removed, for instance. Vagotomy causes a decrease in peristalsis and a change in the emptying patterns of the stomach. To ease this, a pyloroplasty is often performed. This procedure widens the outlet from the stomach to the small intestine.

Preparation

A gastroscopy and x rays of the gastrointestinal system are performed as diagnostic procedures to determine the position and condition of the ulcer. Standard preoperative blood and urine tests are done. The patient should discuss with the anesthesiologist any medications or conditions that might affect the administration of anesthesia.

Aftercare

Patients who have had a vagotomy stay in the hospital for about seven days. For the first three or four days, nasogastric suctioning is required. A tube is inserted through the nose and into the stomach. The stomach contents are then suctioned out. Patients eat a clear liquid diet until the gastrointestinal tract is functioning again. When patients return to a regular diet, spicy and acidic food should be avoided.

It takes about six weeks to fully recover from the surgery. The sutures that close the skin can be removed in seven to ten days. Patients are encouraged to move around soon after the operation to prevent the formation of deep vein blood clots. Pain medication, stool softeners, and antibiotics may be prescribed following the operation.

Risks

As with all surgery, excessive bleeding and infection are possible complications. In addition, the emptying patterns of the stomach are changed. This can lead to dumping syndrome and diarrhea. Dumping syndrome is a condition where shortly after eating, the patient experiences palpitations, sweating, nausea, cramps, vomiting, and diarrhea.

Normal results

Normal recovery is expected for most patients. In about 10% of those who have vagotomy without stomach removal, ulcers recur. Two to three percent of patients who have some portion of their stomach removed also have recurrent ulcers.

Key Terms

Duodenum
The section of the small intestine immediately after the stomach.
Peristalsis
The rhythmic contractions that move material through the bowel.

Further Reading

For Your Information

    Books

  • Way, Lawrence W. "Stomach and Duodenum." In Current Surgical Diagnosis and Treatment, 10th ed., Norwalk, CT: Appleton & Lange, 1994. 479-83.

Gale Encyclopedia of Medicine. Gale Research, 1999.

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