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HIDS

Hyperimmunoglobinemia D with recurrent fever (commonly abbreviated as HIDS) is a syndrome originally described in 1984 by the internist (now Professor) Jos van der Meer at Leiden University Medical Centre. No more than 300 cases have been described worldwide. more...

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Features

HIDS is one of a number of periodic fever syndromes. It is characterised by attacks of fever, arthralgia, skin lesions, and diarrhea. Laboratory features include an acute phase response (elevated CRP and ESR) and markedly elevated IgD (and often IgA), although cases with normal IgD have been described.

Therapy

The recurring fevers are highly unpleasant for patients, but so far only the immunosuppressant etanercept (Enbrel®) has been shown to be effective. Statin drugs might decrease the level of mevalonate and are presently being investigated.

Cause

Virtually all patients with the syndrome have mutations in the gene for mevalonate kinase, which is part of the HMG-CoA reductase pathway, an important cellular metabolic pathway. Indeed, similar fever attacks (but normal IgD) have been described in patients with mevalonic aciduria - an inborn error of metabolism now seen as a severe form of HIDS.

Pathophysiology

Is it not known how mevalonate kinase mutations cause the febrile episodes, although it is presumed that other products of the cholesterol biosynthesis pathyway, the prenylation chains (geranylgeraniol and farnesol) might play a role.

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Group Offers to Sell Supposed Dragon IDS Code
From eWEEK, 7/13/04 by Dennis Fisher

A group calling itself the Source Code Club is offering to sell files that it claims contain the source code for Enterasys Networks Inc.'s Dragon IDS (intrusion detection system) software. The asking price: $16,000.

The group's rudimentary Web site, which is registered under a Ukrainian domain name, lists hundreds of files that appear as though they could indeed be source-code files. There is no way to tell whether the group actually has the code, although it claims to have obtained it by breaking into the Enterasys network.

Officials at Enterasys, based in Andover, Mass., were unaware of the group's site when asked to comment and said they would review the site.

The group also claims to have the source code for the Napster client and server software, which it is offering for sale at $10,000.

Someone using the name Larry Hobbles posted a message to the Full Disclosure security mailing list Monday night saying that both the Dragon and Napster code were available for sale.

"The Source Code Club is now open for business. SCC is a business focused on delivering corporate intel to our customers. Our main focus is selling source code and design documents, but there are many other facets to our business," the message reads. "To get the ball rolling, we are now offering the souce [sic] code/design docs for both Enterasys Intrusion Detection System (NIDS/HIDS) and Napster server and clients."

The files listed on SCC's site appear to be from version 6.1 of Dragon; the current release is 6.3.

For insights on security coverage around the Web, check out eWEEK.com Security Center Editor Larry Seltzer's Weblog.

In an e-mail interview, the SCC member who posted the message to Full Disclosure said the group is made up of professional hackers who are simply in it for the money.

"The Enterasys and Napster code were both acquired via a remote penetration of said corporate networks. SCC is not worried about the legal consequences of such actions for a number of reasons: 1) The countries where we originate from do not have hacking laws. 2) Our team has over 10 years in the information security industry. We know what we are doing," he said.

"Our motivation for selling the property is money and to put our skills to use. We do not only offer source code; there are many hacking services that we provide. We do not wish to continue offering source code publicly, but it is something that must be done initially to ensure the public that we are real."

Both the message and the group's Web site provide an e-mail address registered to a South African domain. The group's site says customers have the option of buying the code all at once or in smaller chunks, which supposedly allows the buyer to verify the authenticity of the code before committing to buying the entire archive.

Dragon is Enterasys' flagship security product and is one of the more popular and well-regarded IDS systems on the market. It is both a network and host IDS.

Check out eWEEK.com's Security Center at http://security.eweek.com for security news, views and analysis. Be sure to add our eWEEK.com security news feed to your RSS newsreader or My Yahoo page:  

Copyright © 2004 Ziff Davis Media Inc. All Rights Reserved. Originally appearing in eWEEK.

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