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Hypothermia

Hypothermia is a medical condition in which the victim's core body temperature has dropped to significantly below normal and normal metabolism begins to be impaired. This begins to occur when the core temperature drops below 35 degrees Celsius (95 degrees Fahrenheit). If body temperature falls below 32 °C (90 °F), the condition can become critical and eventually fatal. Body temperatures below 27 °C (80 °F) are almost uniformly fatal, though body temperatures as low as 14 °C (57.5 °F) have been known to survive. The opposite condition, where temperature is too high, is hyperthermia. more...

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For unknown reasons, people who fall critically unconscious (and arguably die, though there are some who argue that any reversible condition is not, by definition, death) in very cold water can, in rare cases, be resuscitated, even though they would be expected to have died of drowning and/or hypothermia. See Mammalian diving reflex.

Types

There are three types of hypothermia, acute, subacute, and chronic.

  • Acute hypothermia is the most dangerous; the body temperature drops very swiftly, often in a matter of seconds or minutes, such as when a victim falls through an ice-covered lake.
  • Subacute hypothermia occurs on a scale of hours, most commonly by remaining in a cold environment for an extended period of time.
  • Chronic hypothermia is typically caused by an underlying disease.

Symptoms

  • Amnesia
  • Ataxia
  • Cold skin, even in torso
  • Confusion, progressing to delirium
  • Diuresis
  • Dysarthria
  • Gray complexion (pallor)
  • Hypokinesia
  • Increased muscle tone
  • Low blood pressure (hypotension)
  • Peripheral cyanosis
  • Rapid breathing (tachypnea) and heart rate (tachycardia), slowing and weakening as temperature decreases
  • Shivering
  • Tremor
  • Uncontrollable bleeding due to reduced coagulation enzyme activity
  • Weakness

Treatment

Treatment for hypothermia involves raising the core body temperature of the victim.

The first aid response to someone experiencing hypothermia, however, must be made with caution.

  • Do not rub or massage the casualty
  • Do not give alcohol
  • Do not treat any frostbite
  • Do not allow the body to become vertical

Any of these actions will divert blood from the critical internal organs and will worsen the situation.

What you should do:

  • Call the emergency services
  • Get the patient to shelter
  • If possible, put the patient in a bath with medium-temperature water, with the clothes on
  • Place hot water bottles (wrapped in a cotton sock) in the patient's armpits and between their legs
  • Give food and warm drinks
  • Monitor the patient and be prepared to give Cardio-pulmonary resuscitation.
  • Remove wet clothing if and only if a dry change is available

If the hypothermia has become severe, notably if the patient is incoherent or unconscious, re-warming must be done under strictly controlled circumstances in a hospital. Bystanders should only remove the patient from the cold environment, give warm drinks (not too warm because it can lead to temperature shock) and get the patient to advanced medical care as quickly as possible.

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Hypothermia-related deaths—United States, 2003
From Morbidity and Mortality Weekly Report, 3/5/04 by S. Shapiro

Hypothermia, a preventable lowering of the core body temperature to <95[degrees] F (<35[degrees] C) (1), causes approximately 600 deaths each year in the United States (2). Exposure to excessive cold (or excessive exposure to cold) slows enzymatic activity throughout the body, leading to potentially fatal rhabdomyolysis, coagulopathy, renal failure, and dysrhythmias (3). Alcohol intake, activity level, and type of clothing are among the modifiable factors associated with hypothermia (4). Understanding the epidemiology and pathophysiology of hypothermia is important to preventing hypothermia-related mortality. This report describes three cases of fatal hypothermia that occurred during 2003, reviews national statistics on mortality from cold exposure in 2001, and provides recommendations for the diagnosis, treatment, and prevention of hypothermia. Public health strategies tailored to U.S. populations at increased risk for exposure to excessive cold can help reduce mortality and morbidity from hypothermia.

Case Reports

Case 1. In the fall of 2003, a man aged 44 years was found dead outdoors in Vermont. He wore a T-shirt, long-sleeved shirt, two sweatshirts, underpants, pants, socks, and boots. His clothes were wet, and an empty vodka bottle was nearby. Local investigators reported that he looked as though he "lay down and went to sleep." Overnight, the temperature had dropped to <32[degrees] F (<0[degrees] C). Autopsy findings were unremarkable except for a fatty liver. A toxicology screen was negative except for an elevated blood alcohol concentration (BAC) of 0.30 g/dL, nearly four times the legal intoxication limit of 0.08 g/dL in Vermont. Cause of death was certified as hypothermia, with alcohol intoxication as a contributing factor.

Case 2. In the spring of 2003, a man aged 76 years with Alzheimer's disease was reported missing from his home in Vermont. The next day, a farmer found the man lying in a swampy area where his car had become stuck in the mud. Overnight, the temperature had dropped to <32[degrees]F (<0[degrees]C). The man was pronounced dead at the scene; cause of death was hypothermia precipitated by a cold, wet environment.

Case 3. In the fall of 2003, Alaska state troopers reported that a hiker aged 35 years was found dead alongside a highway. The hiker was not clothed from the waist up and was missing a shoe. The overnight temperature was 44[degrees]F (6.7[degrees]C), but conditions were wet and windy. The hiker's BAC was 0.28 g/dL, nearly four times the legal intoxication limit of 0.08 g/dL in Alaska; his toxicology screen was positive for cocaine and marijuana. Cause of death was hypothermia, with drug and alcohol intoxication as contributing Factors.

United States

In the United States, certain populations (e.g., alcoholics; drug users; elderly, homeless, and chronically ill persons; and those with preexisting heart disease) are at increased risk for dying from hypothermia. During 2001, a total of 599 persons in the United States (2) died from "exposure to excessive natural cold" (code X31), as categorized in the International Classification of Diseases, Tenth Revision. Of these victims, 67% were male, and 51% were aged >65 years. As persons age, their risk for dying from hypothermia increases (Figure). Approximately 71% of the hypothermia-related deaths in 2001 occurred during November-February. The three states with the highest rates of death from hypothermia were Montana (1.44 persons per 100,000 population), Alaska (1.42), and New Mexico (1.04).

References

(1.) Yoder E. Disorders due to heat and cold [Chapter 97]. In: Bennett JC, ed. Cecil Textbook of Medicine, 21st ed. Philadelphia, Pennsylvania: WB Saunders Company, 2000.

(2.) National Center for Health Statistics. Compressed mortality file. Hyattsville, Maryland: U.S. Department of Health and Human Services, CDC, National Center for Health Statistics, 2003.

(3.) U.S. Census Bureau. Census 2000 Redistricting (Public Law 94-171) Summary File, Table PL1. Available at http://www.census.gov.

(4.) CDC. Extreme cold: a prevention guide to promote your personal health and safety. Atlanta, Georgia: U.S. Department of Health and Human Services, CDC, 2003. Available at http://www.cdc.gov/nceh/hsb/ extremecold.

(5.) American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA 1992;68:2171-302.

(6.) The Eurowinter Group. Cold exposure and winter mortality from ischaemic heart disease, cerebrovascular disease, respiratory disease, and all causes in warm and cold regions of Europe, 1997. Lancet 1997;349:1341-6.

Editorial Note: Hypothermia causes multiple dysfunctions, including cardiac arrhythmias, renal insufficiency, and hemo-concentration. In late stages of hypothermia, brain function deteriorates, predisposing persons to poor judgment and increasing their risk for further exposure to excessive cold.

Improper clothing and comorbidities can interfere with the balance between the body's heat production and cooling. Wet clothing cannot retain body heat; warm clothing keeps the body dry and helps to decrease heat loss, which can save a person's life during excessively cold weather. Advanced age, immobility, and existing medical conditions can increase the risk for hypothermia and death during cold weather. Certain medical conditions (e.g., hypothyroidism, congestive heart failure, and diabetes) can affect a person's ability to recognize warning symptoms of hypothermia, compensate for the cold, or to seek shelter from the cold.

Use of alcohol or other mood-altering drugs often is associated with cases of hypothermia. The vasodilatation caused by alcohol provides a sensation of warmth but also increases heat loss through radiation. In addition, alcohol and other drugs impair hand coordination, mobility, and decision-making abilities.

Treatment of hypothermia focuses on returning the core body temperature to normal while providing supportive care. The method chosen to rewarm a patient depends on the severity of the hypothermia (Box). With rewarming and supportive care, even persons who appear to be dead might survive hypothermia (5).

Prevention of hypothermia requires public health strategies that target persons at greatest risk. Such strategies can include creating community programs for checking on the well-being of elderly persons, opening temporary shelters for the homeless, and urging persons with cardiovascular disease to avoid outdoor exercise during cold weather (6).

BOX. Epidemiology, diagnosis, treatment, prevention, and reporting of hypothermia

Epidemiology

* Hypothermia is caused by exposure to excessive cold (or excessive exposure to cold).

* Hypothermia can occur in temperatures above freezing.

* Hypothermia disproportionately affects the elderly, homeless, and chronically ill, and persons with preexisting heart disease.

* Immersion in water, wearing wet clothing, and exposure to wind can accelerate body heat loss.

* Mood-altering substances (e.g., alcohol and drugs) impair judgment and are associated with mortality from hypothermia.

Clinical findings

* Symptoms of hypothermia include sensation of cold, exhaustion, and numbness.

* Signs of hypothermia include shivering, pallor in adults, flushed skin in children, decreased hand coordination, confusion, and slurred speech.

* Diagnosis is made when the core body temperature is <95.0[degrees] F (<35.0[degrees] C).

* Hypothermia can be mild (90.0[degrees] F-<95.0[degrees] F [32.2[degrees] C<35.0[degrees] C]), moderate (82.5[degrees] F-90.0[degrees] F [28.0[degrees] C-32.2[degrees] C]), or severe (<82.5[degrees] F [<28.0[degrees] C]).

Treatment

* Mild hypothermia can be treated with passive rewarming by using blankets.

* Moderate hypothermia requires active rewarming with warm intravenous fluids, oxygen, lavage, or immersion baths.

* Severe hypothermia might require both active rewarming and cardiopulmonary bypass.

* The core body temperature should be rewarmed by 2-4[degrees] F (1-2[degrees] C) per hour.

* As needed, cardiopulmonary resuscitation and supportive care should be provided, cardiac rhythm monitored, and electrolytes replenished.

Prevention and reporting

* The public should be educated about the danger of using alcohol and drugs in excessive cold.

* During cold weather, infants, elderly neighbors, and homeless populations should be monitored.

* Instructions should be provided on how to prepare emergency kits for homes and cars and how to safely use an alternate heat source (http://www.cdc.gov/nceh/hsb/ extremecold).

* Any cases of hypothermia should be reported to the local health department.

Reported by: S Shapiro, MD, P Morrow, MD, Vermont Dept of Health F Fallico, MD, Alaska Dept of Health and Social Svcs. E Azziz Baumgartner, MD, EIS Officer, CDC.

COPYRIGHT 2004 U.S. Government Printing Office
COPYRIGHT 2004 Gale Group

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