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Lantus

Lantus is a long-acting basal insulin analogue, usually given once or twice daily to help control the blood sugar level of those with diabetes. Its theoretical advantage is that it has a 24 hour duration of action, with a "peakless" profile. Thus, it more closely resembles the basal insulin secretion of the normal pancreatic beta cells. In type 2 diabetes and in combination with a short acting sulphonylurea (drugs which stimulate the pancreas to make more insulin), it can offer moderate control of serum glucose levels. more...

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In the absence of endogenous insulin (Type 1 diabetes or depleted type 2), Lantus needs the support of a fast acting insulin taken with food to reduce the effect of prandially derived glucose. It is post-prandial glucose elevation which more significantly affects HbA1c and thus determines the progression of the long-term complications of diabetes mellitus.

The peakless profile of Lantus also enables the dose to be relatively higher than standard NPH insulin. Because standard NPH is normally administered at night, its peak of action tends to coincide with the lower serum glucose levels associated with nocturnal metabolism. This can induce nocturnal hypoglycaemia. Lantus offers the benefit of a more consistent pharmacological dynamic without nocturnal hypoglycaemia. The result of this is a patient who feels more confident and more comfortable with a lower pre-bed and pre-breakfast capillary glucose level.


Lantus is formulated at pH4, whereby it is completely soluble. Upon injection, it is neutralized leading to the release small precipitates. This ensures that small amount of Lantus is released into the body continuously, giving a peakless profile

Read more at Wikipedia.org


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Friends 50 and over
From Diabetes Forecast, 10/1/05

SHERRI COOPER, 53, has had type 2 diabetes since 1999. She's also bipolar and suffers from depression. Her hobbies include watching movies and doing activities with her friends. Cooper has a cat named Sweety Pie. No chain letters or inmates, please (P.O. Box 1705, Carterville, GA 30120).

KATIE GOLDHAHN, 54, has type 2 diabetes. She enjoys writing letters, meeting new people, and taking long walks. Goldhahn would love to hear from others (426 S. Springfield Road, Apt. H 11, Clifton Heights, PA 19018).

DONNA JANOWSKI, 54, has had diabetes for 1 year. She takes Avandia and glyburide and is on insulin. She has a hard time controlling her diabetes. Janowski's interests include walking, reading, going on the computer, and doing hospice work (4donna2ron@gwi.net).

SANDRA MERCADO, 54, has had type 2 diabetes for 4 years. She takes oral medication and insulin twice a day. She loves reading Diabetes Forecast. Mercado will respond to all letters (P.O. Box 666, Wylie, TX 75098).

JOANIE RUSHING, 54, has had type 2 diabetes for over 15 years and has a difficult time getting her blood glucose below 150. Her hobbies are reading, watching TV, going to garage sales, and talking with friends on the phone. She would love to hear from others. No inmates, please (P.O. Box 222, Quinlan, TX 75474).

RANDALL VOSBURGH, 55, has had type 2 diabetes for 10 years. He controls his diabetes with diet and insulin. Although he has neuropathy he tries to walk as much as possible, weather permitting. Vosburgh enjoys listening to the radio and watching movies, PBS shows, and science fiction programs. He also likes writing poetry, drawing, and painting. He would like to correspond with others over the age of 45 (30 Brookhaven Dr., Cheektowaga, NY 14225; randallvosburgh@yahoo.com).

JO ANNE PLEMMONS, 56, has type 2 diabetes. She is not married and is a Christian. Plemmons enjoys animals, playing with her pets, going to the movies, cooking vegetarian dishes, and spending time with her grandchild. She would like to hear from both male and female friends, especially those who live in Southern California (225 South Wanda Dr., Fullerton, CA 92833).

EMMA JOHNSON, 57, has type 2 diabetes and has neuropathy. She takes Avandia and Starlix. She collects angels, butterfly stickers, and bells. She loves to listen to old country music. Johnson has four grandchildren, and she was Amish at one time (14763 Northern Dr., Apt. B7, Middlefield, OH 44062).

JANET WILCOX, 58, has type 2 diabetes. She takes two shots daily and is having trouble keeping her blood glucose in a normal range. Wilcox likes writing letters and going on her computer. No chain letters or inmates, please (52 Lafayette St., #2, Waterloo, IA 50703).

NADINE BAKER, 60, has had type 2 diabetes since March 1994. She used to be on oral medications but now takes insulin, which has resulted in better blood glucose readings. Baker is divorced and has one daughter, one son, and two granddaughters. She enjoys doing word puzzles and collecting butterflies. She will answer all letters (P.O. Box 612, Justin, TX 76247).

JOANNE E. PAIGE, 60-something, was diagnosed with type 2 diabetes in 2004. Since her diagnosis, her clothing size went from 14 to a size 8 and her blood glucose readings and A1Cs have improved. She also has osteoporosis, osteoarthritis, and osteopenia. With her faith in the Lord and her determination, Paige hopes to stay medication-free. She would like to hear from others with diabetes. No chain letters or inmates, please (P.O. Box 2621, Lakeland, FL 33840).

SANDY RAYMOND, 65, has had type 1 diabetes since 1950 and has been on the pump since 1998. Raymond is a grandmother. She would like to hear from people who attended Camp NYDA in Burlingham, N.Y., during the summers of 1951 through 1954. Camp NYDA no longer exists, but going to the camp taught her that she wasn't the only child in the world who had diabetes at a time when diabetes was a thing you didn't tell anyone about. No inmates, please (E-mail: Sunni4011@yahoo.com).

MAE HARAKAL, 76, has had diabetes for at least 15 years. She takes medications and is having a hard time controlling her blood glucose. Harakal is a widow. Her interests include going to auctions, thrift shops, and garage sales, baking, making crafts, and participating in senior-related activities (513 Second St., Catasauqua, PA 18032).

PHILIP LYNCH, 76, has had type 1 diabetes since 1974. He takes 23 units of Lantus daily. Lynch watches TV each night and enjoys wine. He enjoys cooking three simple meals a day (33 Cedar Dr., Miller Place, NY 11764).

COPYRIGHT 2005 American Diabetes Association
COPYRIGHT 2005 Gale Group

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