Metoprolol is a selective beta1 receptor blocker used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor® by Novartis, and Toprol® (in the USA), Seleken® or Selokeen® (elsewhere) by AstraZeneca and as Corvitol® by Berlin-Chemie AG. more...
It should be noted that Lopressor® refers to metoprolol tartrate, while Toprol® refers to metoprolol succinate.
- Without intrinsic sympathomimetic activity (ISA)
- Without membrane stabilizing activity
- Short half-life must be taken at least twice daily or SR preparations
- Essential hypertension
- Coronary heart disease (prevention of angina attacks)
- Secondary prevention after a myocardial infarction
- Low dosed treatment of some forms of heart failure (see MERIT-HF study1)
- Migraine prophylaxis
- Adjunct in treatment of hyperthyroidism
In the United States and most other countries, this medication is available only by prescription.
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