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Prostatitis

Prostatitis is any form of inflammation of the prostate gland. Because women do not have a prostate gland, it is a condition only found in men. more...

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Prostatitis may account for up to 25 percent of all office visits by young and middle-age men for complaints involving the genital and urinary systems.

Signs and symptoms

Inflammation of the prostate leads to pain, often during voiding but also in back and rectum. Frequent urination and increased urgency may suggest a cystitis (bladder infection). Ejaculation may be painful, as the prostate contracts during emission of semen.

Diagnosis

If prostatitis is suspected, urinalysis may show white blood cells, red blood cells, nitrite positivity and microorganisms. This is mainly so in acute prostatitis and asymptomatic inflammatory prostatitis (see below). In the other types, urinalysis may be unhelpful.

Prostate specific antigen levels may be elevated, although there is no malignancy. In acute prostatitis, a full blood count reveals increased white blood cells. Sepsis from prostatitis is very rare, but may occur in immunocompromised patients; high fever and malaise generally prompt blood cultures, which are often positive in sepsis.

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More on quercetin and chronic prostatitis - Literature Review & Commentary - Brief Article
From Townsend Letter for Doctors and Patients, 5/1/02 by Alan R. Gaby

In a previous uncontrolled trial reviewed in the Townsend Letter, quercetin was found to relieve symptoms in a large proportion of patients with chronic bacterial prostatitis, chronic non-bacterial prostatitis, and prostatodynia. This preliminary report has now been followed up by a controlled trial. Thirty men with category IIIa or IIIb chronic pelvic pain syndrome (chronic nonbacterial prostatitis and prostatodynia; mean duration of symptoms, 11 years) were randomly assigned to receive, in double-blind fashion, quercetin (500mg twice daily) or placebo for one month. The NIH chronic prostatitis symptom score was used to grade symptoms and quality of life. In the placebo group, the mean NIH symptom score improved by 7.1%, compared with a 37.6% improvement in the quercetin group (p = 0.003). The proportion of patients experiencing at least a 25% improvement (the amount considered clinically meaningful) was 20% in the placebo group and 67% in the quercetin group (p = 0.001).

Comment: The results of this study suggest that supplementation with quercetin resulted in significant symptomatic improvement in men with chronic pelvic pain syndrome. It should be noted that two of the four authors of this study own stock in companies that would benefit from sales of the supplements used in the study. Therefore, it would be useful to see this study repeated by another research group.

Shoskes DA, et al. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology 1999;54:960-963.

COPYRIGHT 2002 The Townsend Letter Group
COPYRIGHT 2002 Gale Group

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