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Squamous cell carcinoma

In medicine, squamous cell carcinoma is a form of cancer of the carcinoma type that may occur in many different organs, including the skin, the esophagus, the lungs, and the cervix. It is a malignant tumour of epithelium that shows squamous cell differentiation. more...

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Squamous cell carcinomas account for about 20% of non-melanoma skin cancers, (with basal cell carcinomas accounting for about 80%), but are clinically more significant because of their ability to metastasize. Squamous cell carcinoma is usually developed in the epithelial layer of the skin and sometimes in different mucous membranes of the body. This type of cancer can be seen on the skin, lips, inside the mouth, throat or esophagus. This type of cancer is characterized by red, scaly skin that becomes an open sore.

Squamous cell carcinoma strikes more than 200,000 people in the United States alone every year.

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ZD1839 for recurrent or metastatic squamous cell carcinoma of the skin - Iressa® - Clinical Trial Review - Brief Article
From Journal of Drugs in Dermatology, 10/1/03

This study is not yet open for patient recruitment.

Sponsored by M.D. Anderson Cancer Center

This is a Phase II trial to determine the effectiveness of 250 mg ZD1839 daily by mouth for 6 courses of treatment (1 course = 4 weeks) to determine its effectiveness on treating recurrent or metastatic squamous cell carcinoma of the skin.

Study ID Numbers: ID02-282

NLM Identifier: NCT00054691

COPYRIGHT 2003 Journal of Drugs in Dermatology
COPYRIGHT 2003 Gale Group

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