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Topicort

Brand name is : Topicort
Pronounced: TOP-i-court
Generic name: Desoximetasone
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This medication belongs to the family of medications known as topical corticosteroids. It is used for the relief of various skin conditions, including rashes. It helps to reduce redness, itching, and irritation.

There are two brand name products;

Topicort® Emollient Cream(desoximetasone) 0.25%
Topicort® LP Emollient Cream (desoximetasone) 0.05%

Topicort® (desoximetasone) Emollient Cream 0.25% and Topicort® LP (desoximetasone) Emollient Cream 0.05% both contain the active synthetic corticosteroid desoximetasone. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents.

Each gram of TOPICORT Emollient Cream 0.25% contains 2.5 mg of Desoximetasone in an emollient cream consisting of White Petrolatum USP, Purified Water USP, Isopropyl Myristate NF, Lanolin Alcohols NF, Mineral Oil USP, Cetostearyl Alcohol NF, Aluminum Stearate, and Magnesium Stearate.

Each Gram of TOPICORT LP Emollient Cream 0.05% contains 0.5 mg Desoximetasone in an emollient cream consisting of White Petrolatum USP, Purified Water USP, Isopropyl Myristate NF, Lanolin Alcohols NF, Mineral Oil USP, Cetostearyl Alcohol NF, Aluminum Stearate, Edetate Disodium USP, Lactic Acid USP and Magnesium Stearate.

The chemical name of desoximetasone is Pregna-1, 4-diene-3, 20-dione, 9-fluoro-11, 21-dihydroxy-16-methyl-, (11β, 16α)-. Desoximetasone has the empirical formula C22H29FO4 and a molecular weight of 376.47. The CAS Registry Number is 382-67-2.

Uses

When you use Topicort, you may absorb some of the medication through your skin and into the bloodstream. Too much absorption can lead to unwanted side effects elsewhere in the body. To keep this problem to a minimum, avoid using large amounts of Topicort over large areas, do not use it for extended periods of time, and do not cover it with airtight dressings such as plastic wrap or adhesive bandages unless specifically told to by your doctor.

Children may absorb more medication than adults do. Topicort is for use only on the skin. Be careful to keep it out of your eyes. Apply a thin coating of Topicort to the affected area. Rub in gently. The treated area should not be covered unless your doctor has told you to do so.

If Topicort is being used for an infant or toddler with a genital rash, make sure the diapers or plastic pants are not too tight, so that air can circulate.

-If you miss a dose... Use Topicort only as needed, in the smallest amount required for relief. -Storage instructions... Store Topicort at room temperature.

Reference Links

Topicort general info
Topicort usage info

Read more at Wikipedia.org


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Medicis to Present at JP Morgan 21st Annual Healthcare Conference
From Business Wire, 12/30/02

Business Editors, Pharmaceutical Writers

SCOTTSDALE, Ariz.--(BUSINESS WIRE)--Dec. 30, 2002

Medicis (NYSE:MRX) today announced that a live webcast of its presentation scheduled for Monday, January 6, 2003, at 10 a.m. Pacific Time (1 p.m. Eastern Time), may be accessed via the Internet.

Medicis is scheduled to present at the JP Morgan 21st Annual Healthcare Conference at the Westin St. Francis Hotel in San Francisco.

The webcast will be available via a link on the Medicis corporate web site at http://www.medicis.com/ir/index.html. This link will allow visitors to the web site to access the Medicis presentation. An archive of the webcast will be available on the Medicis corporate web site for two business days following the live presentation.

Medicis is the leading independent specialty pharmaceutical company in the United States focusing primarily on the treatment of dermatological, pediatric and podiatric conditions. Medicis has leading prescription products in a number of therapeutic categories, including acne, asthma, eczema, fungal infections, head lice, hyperpigmentation, photoaging, psoriasis, rosacea, seborrheic dermatitis and skin and skin-structure infections. The Company's products have earned wide acceptance by both physicians and patients due to their clinical effectiveness, high quality and cosmetic elegance.

The Company's products include the prescription brands DYNACIN(R) (minocycline HCl), LOPROX(R) (ciclopirox), LUSTRA(R) (hydroquinone), LUSTRA-AF(R) (hydroquinone) with sunscreen, ALUSTRA(R) (hydroquinone) with retinol, OMNICEF(R) (cefdinir), ORAPRED(R) (prednisolone sodium phosphate), OVIDE(R) (malathion), PLEXION(R) Cleanser (sodium sulfacetamide/sulfur), PLEXION TS(R) (sodium sulfacetamide/sulfur), PLEXION SCT(R) (sodium sulfacetamide/sulfur), TRIAZ(R) (benzoyl peroxide), LIDEX(R) (fluocinonide), SYNALAR(R) (fluocinolone acetonide) and TOPICORT(R) (desoximetasone); the over-the-counter brand ESOTERICA(R); and BUPHENYL(R) (sodium phenylbutyrate), a prescription product indicated in the treatment of Urea Cycle Disorder.

Except for historical information, this press release includes "forward-looking statements" within the meaning of the Securities Litigation Reform Act. All statements included in this press release that address activities, events or developments that Medicis expects, believes or anticipates will or may occur in the future are forward-looking statements. This includes earnings estimates, future financial performance and other matters. These statements are based on certain assumptions made by Medicis based on its experience and perception of historical trends, current conditions, expected future developments and other factors it believes are appropriate in the circumstances. The Company cannot validate its assumptions of the full impact on its business of the approval of competitive generic versions of the Company's core brands, or any future competitive product approvals that may affect the Company's brands. Such statements are subject to a number of assumptions, risks and uncertainties, many of which are beyond the control of Medicis. Any such projections or statements include the current views of Medicis with respect to future events and financial performance. No assurances can be given, however, that these events will occur or that such results will be achieved and there are a number of important factors that could cause actual results to differ materially from those projected, including the ability to realize anticipated synergies and benefits of the Ascent transaction, the risks and uncertainties normally incident to the pharmaceutical industry, dependence on sales of key products, the uncertainty of future financial results and fluctuations in operating results, dependence on Medicis' strategy including the uncertainty of license payments and/or other payments due from third parties, the timing and success of new product introductions and other risks described from time to time in Medicis' SEC filings including its Annual Report on Form 10-K for the year ended June 30, 2002. In addition, Medicis recently sold $400 million of 2.5% Contingent Convertible Notes Due 2032. There can be no assurance as to when or if any of the Notes will be converted, and what impact the increase in the number of shares outstanding will have on our results of operations. Forward-looking statements represent the judgment of Medicis' management as of the date of this release, and Medicis disclaims any intent or obligation to update any forward-looking statements.

NOTE: Full prescribing information for any Medicis prescription product is available by contacting the Company. OMNICEF(R) is a registered trademark of Abbott Laboratories, Inc. under a license from Fujisawa Pharmaceutical Co., Ltd. All other marks (or brands) and names are the property of Medicis or its Affiliates.

COPYRIGHT 2002 Business Wire
COPYRIGHT 2002 Gale Group

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