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Vivelle

The estrogen patch is a delivery system for estradiol used as hormone replacement therapy to treat the symptoms of menopause, such as hot flashes and vaginal dryness, and to prevent osteoporosis. Originally marketed as VivelleĀ® (Novartis), it was discontinued in 2003 and reintroduced in a smaller form as Vivelle-DotĀ®. Although the estrogen is given transdermally rather than in the standard oral tablets, the estrogen patch carries similar risks and benefits as more conventional forms of estrogen-only hormone replacement therapy.

Administration

Applied to the skin (not breasts) twice weekly.

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Novogyne Pharmaceuticals - Branded News - New postmenopausal osteoporosis treatments - Government Activity - International Pages - Brief Article - Product
From Drug Store News, 6/17/02

The Vivelle-Dot (estradiol transdermal system) in a dosage strength of 0.025 mg/day has been newly approved as a treatment for postmenopausal osteoporosis. The Dot's original dosage strengths also received the new indication. It is applied to the abdomen two times a week and can been worn during normal activities and exercise.

Vivelle-Dot is made by Novogyne Pharmaceuticals, a join venture between Novartis and Noven Pharmaceuticals. The 0.025 mg/day version, the lowest dosage, is expected to be available this August.

In addition, Procter & Gamble and Aventis also have introduced a new osteoporosis offering: a once-a-week version of Actonel (risedronate sodium tablets) 35 mg for the prevention and treatment of postmenopausal osteoporosis. It was expected to be available by the middle of this month.

COPYRIGHT 2002 Reproduced with permission of the copyright holder. Further reproduction or distribution is prohibited without permission.
COPYRIGHT 2002 Gale Group

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