Whipple's disease is a rare disease caused by the bacteria Tropheryma whipplei. more...
It was first described by George Hoyt Whipple in 1907.
- intestinal lipodystrophy (accumulation of fatty deposits in lymph nodes of the intestine)
- abdominal pain
Diagnosis is made by intestinal biopsy, which shows as PAS-positive macrophage inclusions.
At times, small bowel X-rays may show some thickened folds.
Treatment is with penicillin, ampicillin, tetracycline or co-trimoxazole for 4-6 months.
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