Amlodipine chemical structure
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Amlodipine

Amlodipine (as besylate or malleate) is a long-acting calcium channel blocker used as an anti-hypertensive and in the treatment of angina. Amlodipine is marketed as Norvasc® and under various other names. As other calcium channel blockers, amlodipine acts by relaxing the smooth muscle in the arterial wall, decreasing peripheral resistance and hence improving blood pressure; in angina it improves blood flow to the myocardium. It was developed under the direction of Dr. Simon Campbell. more...

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Side effects

Some side effects of the use of amlodipine may be:

  • Very often: peripheral edema (feet and ankles) - in 1 of 10 users
  • Often: dizzyness, palpitations, muscle, stomach or headache, dyspepsia, nausea - in 1 in 100 users
  • Sometimes: blood disorders, development of breasts in men (gynecomastia), impotence, depression, insomnia, tachycardia - in 1 in 1,000 users
  • Rarely: erratic behavior, hepatitis, jaundice - in 1 in 10,000 users
  • Very rarely: hyperglycemia, tremor, Stevens-Johnson syndrome - in 1 in 100,000 users

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Amlodipine $158.25 Amlodipine benefits normotensive CAD patients.(News) : An article from: Internal Medicine News $5.95
ARB linked to 20% drop in new-onset diabetes: yielded mortality similar to amlodipine.(News)(angiote nsin receptor blocker) : An article from: Internal Medicine News $5.95

Amlodipine for CAD and normal blood pressure
Clinical Question: Is the administration of amlodipine beneficial for patients with coronary artery disease (CAD) and normal blood pressure? Setting: ...
Do irbesartan and amlodipine reduce cardiovascular events in diabetic patients? - Patient Oriented Evidence That Matters: practice recommendations from
Berl T, Hunsicker LG, Lewis JB, et al. Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt ...
Sumitomo Chemical Files Suit Against Pfizer for Amlodipine Besilate
Tokyo, Japan, Nov 2, 2005 - (JCNN) - Sumitomo Chemical announced on November 1 that it and its subsidiary Dainippon Sumitomo Pharma have jointly filed ...
Effect of amlodipine on insulin resistance & tumor necrosis factor-alpha levels in hypertensive obese type 2 diabetic patients
Background & objectives: Tumour necrosis factor-alpha (TNF-α) has been suggested to play a key role in insulin resistance (IR) in obesity and may contribute ...
Amlodipine Improves The Anti-Ischaemic Effect Of Atenolol In Postinfarctions Patients With Effort - Induced Ischaemia An Echostress Study - Abstract
Purpose: This study was conducted to determine whether amlodipine has an additive anti-ischaemic effect to atenolol in postinfarction patients with stable exercise induced ischaemia. Methods: 35
Influence Of The Calcium Antagonist Amlodipine On Left Ventricular Mass And Function In Patients With Essential Hypertension - Abstract
Purpose: This study was conducted to evaluate the influence of antihypertensive treatment with the calcium antagonist amlodipine on left ventricular ...
A comparative analysis of amlodipine and felodipine in a military outpatient population: Efficacy, outcomes, and cost considerations
Background: This retrospective study compared the efficacy, tolerability, and cost of two dihydropyridine calcium channel blockers. Methods: Charts of ...
Amlodipine lowers blood pressure without affecting cerebral blood flow as measured by single photon emission computed tomography in elderly hypertensive
Aim: to evaluate the effect of amlodipine on blood pressure and cerebral blood flow in elderly subjects with mild to moderate hypertension. Methods: a double-blind, parallel group study of 26 patien

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