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Astemizole

Astemizole is a second generation antihistamine that has a long duration of action.

However, it has been withdrawn from the marketplace in most countries because of rare but potentially fatal interactions with strong CYP34A enzyme inhibitors.

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Acetylcholine chloride

Acetyldigitoxin

Alvircept sudotox

Aminocaproic acid

Aminoglutethimide

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		Astemizole in Asthma $28.90			Astemizole: A new, non-sedative, long-acting Hb1s-antagonist : proceedings of a symposium held in Beerse, Belgium, October, 1983 (The Medicine Publishing Foundation symposium series)


	Astemizole Withdrawn from the Market The antihistamine astemizole (Hismanal) has been voluntarily withdrawn from the market by the manufacturer. Since the approval of the drug by the U.S. From American Family Physician, 8/1/99 by Verna L. Rose

	Single-dose effect of astemizole on bronchoconstriction induced by histamine in asthmatic subjects Chantale Benoit; Jean-Luc Malo, M.D.; Heberto Ghezzo, Ph.D.; and Andre Cartier, M.D. Study Objective: Astemizole, administered for seven days to asthmatic subjects, had an effect of bronchoconst From CHEST, 5/1/92 by Chantale Benoit

	Cardiac effects of astemizole overdose in children - Tips from Other Journals Astemizole is a nonsedating, long-acting antihistamine widely used in the treatment of allergic rhinitis, allergic conjunctivitis, urticaria and chronic ... From American Family Physician, 9/1/92

	Five-day telithromycin once daily is as effective as 10-day clarithromycin twice daily for the treatment of acute exacerbations of chronic bronchitis and Study objectives: To demonstrate equivalence in the clinical efficacy of telithromycin vs clarithromycin treatment of outpatients with acute exacerbations ... From CHEST, 10/1/05 by Charles Fogarty

	Effects of 24 weeks of lansoprazole therapy on asthma symptoms, exacerbations, quality of life, and pulmonary function in adult asthmatic patients with Background: Difficult-to-control asthma has been associated with gastroesophageal acid reflux. Acid-suppressive treatment has been inconsistent in improving ... From CHEST, 9/1/05 by Michael R. Littner

	Pharmacologic agents associated with QT interval prolongation KEY POINTS Diverse classes of medications are associated with QT interval prolongation and expose patients to the risk of potentially fatal ventricular ... From Journal of Family Practice, 6/1/05 by Keith M. Olsen

	Assessment of QT/QTc Interval Prolongation in Clinical Trials: A Regulatory Perspective*, The Excessive prolongation of the QT/QTc interval creates an electrophysiological environment that predisposes the myocardium to torsade de pointes, a polymorphic ... From Drug Information Journal, 1/1/05 by Strnadova, Colette

	Lichen nitidus treated with topical tacrolimus Abstract A 32-year-old Philippino male presented to the clinic with a penile rash of 2 months duration. The rash was diagnosed as lichen nitidus and ... From Journal of Drugs in Dermatology, 11/1/04 by Clifton R. Dobbs

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