Fexofenadine chemical structure
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Fexofenadine

Fexofenadine hydrochloride (brand names include Allegra® and Telfast®) is an antihistamine drug used in the treatment of hayfever and similar allergy symptoms. It was developed as a successor of and alternative to terfenadine, an antihistamine with potentially fatal contraindications. more...

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History

Fexofenadine was developed by Hoechst Marion Roussel (now part of Aventis) and approved by the FDA in 1996. Since that time, it has achieved blockbuster drug status with global sales of $1.87B USD in 2004 (with $1.49B USD coming from the United States).

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Aggressive antihistamine use urged: in children.(Children's Health) : An article from: Family Practice News $5.95 No safety signals seen with pediatric fexofenadine.(Clinical Rounds)(antihistamine) : An article from: Skin & Allergy News $5.95
No new safety signals for fexofenadine in children: few reports over 1 year.(Clinical Rounds) : An article from: Pediatric News $5.95

Teva Pharmaceutical Industries
Teva Pharmaceutical Industries.(approval for Fexofenadine HC1, Tramadol, Acetaminophen and Mirtazapine)
From Drug Store News, 8/22/05
Fexofenadine and prolonged QT intervals
THIS ALLERGY MEDICATION MAY EXACERBATE CARDIAC PROBLEMS A 67-YEAR-OLD MAN who'd been taking 180 mg of fexofenadine (Allegra) daily for 2 months developed ...
From Nursing, 9/1/99 by Shuster, Joel
Mylan Laboratories
Mylan Laboratories.(Generics Notebook)(fexofenadine Hydrochloride and Pseudoephedrine Hydrochloride)
From Drug Store News, 6/21/04
Treating intermittent allergic rhinitis: a prospective, randomized, placebo and antihistamine-controlled study of Butterbur extract Ze 339
BACKGROUND: Intermittent allergic rhinitis (IAR) causes patients distress and impairs their work performance and quality of life. A variety of medicines ...
From Alternative Medicine Review, 12/1/05 by A. Schapowal
Case report: occupationally related recurrent varicella in a hospital nurse
Commonly accepted outcomes of varicella-zoster virus (VZV) infections include chickenpox (primary) and shingles (recurrence or latency), as well lifetime ...
From Environmental Health Perspectives, 10/1/05 by Chih-Hung Ku
Barr Laboratories
Barr Laboratories received final FDA approval for its fexofenadine HC1 capsules in 60 mg strength, the generic version of Aventis Pharmaceuticals' Allegra, ...
From Drug Store News, 8/22/05
Generic substitution spells big money for retail pharmacy
Generic substitution spells big money for retail pharmacy.(GENERIC RX)
From Drug Store News, 8/22/05 by Michelle L. Kirsche
Onslaught of industry issues besieges brands
Onslaught of industry issues besieges brands.(pharmaceutical industry)
From Drug Store News, 8/22/05 by Michael Johnsen

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