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Goiter

A goitre (or goiter) (Latin struma) is a swelling in the neck (just below adam's apple or larynx) due to an enlarged thyroid gland. They are classified in different ways: more...

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  • A "diffuse goitre" is a goitre that has spread through all of the thyroid (and is contrasted with a "simple goitre", "single thyroid nodule" and "multinodular goitre".
  • "Toxic goitre" refers to goitre deriving from inflammation, neoplasm, or malfunction of the thyroid, while "nontoxic goitre" refers to all other types (such as that caused by lithium or an autoimmune reaction.)

Causes

The most common cause for goitre in the world is iodine deficiency (E01). Other causes are:

  • Hashimoto's thyroiditis (E06.3)
  • Graves-Basedow disease (E05.0)
  • juvenile goitre due to congenital hypothyroidism (E03.0)
  • neoplasm of the thyroid
  • thyroiditis (acute, chronic) (E06)
  • side-effects of pharmacological therapy (E03.2)

Occurrence

Iodine is necessary for the synthesis of the thyroid hormones, triiodothyronine and thyroxine (T3 and T4). When iodine is not available, these hormones cannot be made. In response to low thyroid hormones, the pituitary gland releases thyroid stimulating hormone (TSH). Thyroid stimulating hormone acts to try and increase synthesis of T3 and T4, but it also causes the thyroid gland to grow in size as a type of compensation.

Goitre is more common among women. Treatment may not be necessary if the goitre is not caused by disease and is small. Removal of the goitre may be necessary if it causes difficulty with breathing or swallowing.

History and future

Goitre was previously common in many areas that were deficient in iodine in the soil. (For example, in the English Midlands, the condition was known as Derbyshire Neck). The condition now is practically absent in affluent nations, where table salt is supplemented with iodine.

Some health workers fear that a resurgence of goitre might occur because of the trend to use rock salt and/or sea salt, which has not been fortified with iodine.

Read more at Wikipedia.org


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The Thyroid and Its Diseases $69.98 Nutritional Factors Involved in the Geotrogenic Action of Cassava (Idrc (Series), 184e.) $151.40
How to prevent goiter, $28.00 Cost-effective management of thyroid nodules and nodular thyroid goiters. (Featured CME Topic: Thyroid Dysfunction/Disease). : An article from: Southern Medical Journal $5.95
21st Century Complete Medical Guide to Thyroid Diseases, Hyperthyroidism, Goiter, Hypothyroidism, and Graves¿ Disease, Authoritative Government Documents, Clinical References, and Practical Information for Patients and Physicians $25.00 Nontoxic goiter: concept and controversy, $10.00
Thyroid and thymus, $44.95 Gale Encyclopedia of Medicine : Goiter $3.10
A simple cure for an age-old problem. (goiter) : An article from: Medical Update $5.95 The control of goiter;: The thyroid in health and disease, $24.95

Orthopnea and tidal expiratory flow limitation in patients with euthyroid goiter - clinical investigations
Background: Nontoxic goiters can cause extrathoracic upper airway obstruction and, if large, may extend into the thorax, causing intrathoracic airway ...
Goiter
Goiter refers to any visible enlargement of the thyroid gland.
Goiter
Goiter is a swelling in the neck, caused by a malfunction of the thyroid gland.
Supports earlier findings: prevalence of goiter higher in breast Ca patients
LOS ANGELES -- The prevalence of goiter and thyroid antibodies is higher than average in women with breast cancer, Dr. M. Ramazan Sekeroglu and colleagues ...
Flow-Volume Loop Analysis In Different Body Postures Increases The Detection Of Upper Airway Obstruction In Euthyroid Goiter - FVL - UAO - Abstract
Marc Meysman, MD(*); Marc Noppen, MD, PhD; Rika Van Herreweghe, MD; Daniel Schuermans and Walter Vincken, MD, PhD. Resp Division, Dept Medicine, University ...
A case of laryngeal carcinoma appearing as a goiter - Original Article - Brief Article
A case of laryngeal carcinoma appearing as a goiter. (Original Article).
Radioiodine Therapy for Multinodular Goiter
In areas of mild to moderate iodine deficiency, multinodular goiter is a common cause of hyperthyroidism. Because antithyroid medication cannot be expected ...
Please pass the iodine! How a brilliant biologist, a group of schoolchildren, and a school of baby trout shrank America's goiter problem down to size -
Medical researchers had suspected that goiter, a common problem inland in the US but not near the seashore, was related to the lack of iodine in the body.

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