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Goserelin

Goserelin is an injectable gonadotropin releasing hormone agonist (GnRH agonist). It stops the production of sex hormones (testosterone and oestrogen) and is used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction. more...

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It is available as a 1-month depot and a long-acting 3-month depot. Both depots are used for the treatment of prostate cancer, endometriosis and uterine fibroids but only the 1-month depot is approved for breast cancer, endometrial thinning and assisted reproduction.

Goserelin is marketed by AstraZeneca with the brand name Zoladex. It was first launched in 1987 and is currently the second-largest selling LHRHa in the world. It is currently available in more than one hundred markets.

Side effects

Goserelin causes an increase in bone pain and symptoms of prostatic cancer during the first few weeks of treatment. As your body adjusts to the medication, the symptoms will disappear. Goserelin may cause hot flashes, headache, stomach upset, difficulty urinating, weight gain, swelling and tenderness of breasts, decreased erections, reduced sexual desire.

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	Current Therapy for Prostate Cancer: Focus on Goserelin : Proceedings of the Zoladex International Symposium September 20-21, 1991, Kobe, Japan (Cur) $381.88	Gale Encyclopedia of Cancer : Goserelin acetate $2.30

	Goserelin a Viable Option for Early Breast Cancer.(Brief Article) : An article from: Family Practice News $5.95


Goserelin a Viable Option for Early Breast Cancer - Brief Article SAN ANTONIO -- Goserelin is an attractive alternative to adjunctive chemotherapy in many women with early breast cancer, Dr. Walter Jonat said at a breast cancer symposium sponsored by the San Anto From Family Pratice News, 4/1/01 by Bruce Jancin

Goserelin a Good Alternative to Chemotherapy SAN ANTONIO -- Goserelin is an attractive alternative to adjunctive chemotherapy in many women with early breast cancer, Dr. Walter Jonat said at a breast cancer symposium sponsored by the San Anto From OB/GYN News, 3/1/01 by Bruce Jancin

Goserelin acetate Definition Goserelin acetate is a synthetic (man-made) hormone that acts similarly to the naturally occurring gonadotropin-releasing hormone (GnRH). From Gale Encyclopedia of Cancer, by Ed.M. Paul A. Johnson

Mitozantrone-induced onycholysis associated with subungual abscesses, paronychia, and pyogenic granuloma Abstract Chemotherapeutic agents may induce a wide variety of adverse mucocutaneous effects, including nail changes. We present a case of atypical ... From Journal of Drugs in Dermatology, 7/1/05 by Anatoli Freiman

Why get a second pathology opinion for breast cancer: an interview Of all the tests given to a woman newly diagnosed with breast cancer, one is crucial in determining her treatment plan. It measures the tumor's "hormone ... From Healthfacts, 9/1/04

Hormone Treatment Extends Pain-Free Interval Goserelin depot injections lengthened the time to pelvic pain recurrence in women undergoing surgery for symptomatic endometriosis, reported Dr. Paolo ... From OB/GYN News, 10/1/99 by Katherine Arnold

Higher-dose estrogen patch may prevent migraine: after medical oophorectomy - Gynecology CHICAGO -- Dosage maybe an important factor in the use of transdermal estradiol for prevention of headache in female migraineurs, Dr. Vincent T. Martin ... From OB/GYN News, 10/1/03 by Patrice G.W. Norton

AstraZeneca to pay $355 million fine - Updates AstraZeneca Pharmaceuticals LP of Wilmington, Del., has agreed to pay a $355 million fine to resolve criminal charges and civil liabilities stemming ... From FDA Consumer, 9/1/03

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