Chlorhexidine (free base) structure
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Hibiclens

Chlorhexidine Gluconate is an antiseptic used as an active ingredient in mouthwash designed to kill dental plaque and other oral bacteria. In some countries it is available by prescription only. It is sometimes marketed under the brand names Peridex, Periochip, Periogard Oral Rinse or in the UK Corsodyl or Chlorohex. Chlorhexidine Gluconate-based products are usually utilized to combat or prevent gum diseases such as gingivitis. more...

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Chlorhexidine Gluconate is also used in non-dental applications, most notably under the brand name Hibiclens, to combat microbes. It is used for general skin cleansing, a surgical scrub and a pre-operative skin preparation. Due to other chemicals listed as inactive ingredients, Hibiclens is not suitable for use as mouthwash.

Known to be deactivated by fluoride, Chlorhexidine Gluconate mouth rinses should be taken at least 30 minutes after using fluoridated oral products (e.g, toothpaste and mouthwash). For best effectiveness, food, drink, and mouth rinses should be avoided for at least one hour after use. However, mouthwashes formulations containing both chlorhexidine digluconate and fluoride have been found to be effective.

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Handwashing clarification
From Healthcare Purchasing News, 5/1/04 by Dan Manley

To the Editor,

Always at the forefront of emerging topics, Healthcare Purchasing News thoroughly covers important issues for your readers and it is our pleasure to work with your staff to contribute to these articles.

In reviewing the April 2004 article entitled "Surgical Site Infection: The Operation Was a Success, But the Patient Died" by Susan Cantrell, we noticed an error when referencing our product Hibistat. Specifically on page 24 in the issue, it states: "There are still a lot of people who scrub, but the trend is moving toward a hand scrub once with a detergent-based cleansing solution, such as Regent's Hibiclens, followed by a hand rub with an alcohol-based cleanser, such as Hibistat, for each subsequent procedure." Hibistat currently does not have an approved FDA indication for use as a surgical scrub.

We apologize fur not correcting the above statement in our preview, but we wanted to bring this to your attention immediately and apologize for any inconvenience this may cause you.

Regent Medical is dedicated to setting the standard in protection to improve patient outcomes, address glove powder complications and hand-washing techniques and improve latex allergy awareness.

--Sincerely, Dan Manley, Vice President Marketing Regent Medical, SSL Americas, Inc.

COPYRIGHT 2004 Healthcare Purchasing News
COPYRIGHT 2004 Gale Group

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