Find information on thousands of medical conditions and prescription drugs.

Ledderhose disease

Ledderhose's Disease, also known as Morbus Ledderhose, plantar fibromatosis, and plantar aponeurosis, is a non-malignant thickening of the feet's deep connective tissue, or fascia. In the beginning, where nodules or cords start growing along tendons of the foot, the disease is minor, or not painful. Eventually, however, the cords thicken, the toes stiffen and bend, and walking becomes painful. The disease is named after Georg Ledderhose (1855 - 1925), a German surgeon who described the condition for the first time in 1897. more...

Home
Diseases
A
B
C
D
E
F
G
H
I
J
K
L
Amyotrophic lateral...
Bardet-Biedl syndrome
Labyrinthitis
Lafora disease
Landau-Kleffner syndrome
Langer-Giedion syndrome
Laryngeal papillomatosis
Laryngomalacia
Lassa fever
LCHAD deficiency
Leber optic atrophy
Ledderhose disease
Legg-Calvé-Perthes syndrome
Legionellosis
Legionnaire's disease
Leiomyoma
Leiomyosarcoma
Leishmaniasis
Lemierre's syndrome
Lennox-Gastaut syndrome
Leprechaunism
Leprophobia
Leprosy
Leptospirosis
Lesch-Nyhan syndrome
Leukemia
Leukocyte adhesion...
Leukodystrophy
Leukomalacia
Leukoplakia
LGS
Li-Fraumeni syndrome
Lichen planus
Ligyrophobia
Limb-girdle muscular...
Limnophobia
Linonophobia
Lipodystrophy
Lipoid congenital adrenal...
Liposarcoma
Lissencephaly
Lissencephaly syndrome...
Listeriosis
Liticaphobia
Liver cirrhosis
Lobster hand
Locked-In syndrome
Loiasis
Long QT Syndrome
Long QT syndrome type 1
Long QT syndrome type 2
Long QT syndrome type 3
LSA
Lung cancer
Lupus erythematosus
Lyell's syndrome
Lygophobia
Lyme disease
Lymphangioleiomyomatosis
Lymphedema
Lymphoma
Lymphosarcoma
Lysinuric protein...
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Medicines

Ledderhose's disease is the equivalent disease to Dupuytren's disease, which affects the hand and causes bent hand or fingers. As with Dupuytren's disease the root causes of Ledderhose's disease are not yet understood, though an inclination is probably inherited. Men typically get the disease at an earlier age than women. At the age of 80 the probability to suffer from Dupuytren's disease becomes about even for men and women (we have no statistics on Ledderhose's disease), with men typically in a more progressed stage.

Surgery of Ledderhose's disease is difficult because tendons, nerves, and muscles are located very closely to each other. Additionally, feet have to carry heavy load, and surgery might have unpleasant side effects. If the disease has not progressed too far, radiation therapy has proven to relieve and even cure Ledderhose's disease. In some cases shock waves also have been reported to at least reduce pain and enable walking again. Currently in the process of FDA approval is the injection of collagenase.

Therapies of Ledderhose's disease are described on the web site of Dupuytren Society, www.dupuytren-online.info.

Read more at Wikipedia.org


[List your site here Free!]



Peyronie's Disease: Current Management
Peyronie's disease is an acquired inflammatory condition of the penis associated with penile curvature and, in some cases, pain. It primarily affects ...

Home Contact Resources Exchange Links ebay