Metoprolol chemical structure
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Lopressor

Metoprolol is a selective beta1 receptor blocker used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor® by Novartis, and Toprol® (in the USA), Seleken® or Selokeen® (elsewhere) by AstraZeneca and as Corvitol® by Berlin-Chemie AG. more...

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It should be noted that Lopressor® refers to metoprolol tartrate, while Toprol® refers to metoprolol succinate.

Properties:

  • Cardioselective
  • Lipophilic
  • Without intrinsic sympathomimetic activity (ISA)
  • Without membrane stabilizing activity
  • Short half-life must be taken at least twice daily or SR preparations

Indications:

  • Essential hypertension
  • Arrhythmias
  • Coronary heart disease (prevention of angina attacks)
  • Secondary prevention after a myocardial infarction
  • Low dosed treatment of some forms of heart failure (see MERIT-HF study1)
  • Migraine prophylaxis
  • Adjunct in treatment of hyperthyroidism

In the United States and most other countries, this medication is available only by prescription.

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Hypertensive drug classes: brand names only
From Healthfacts, 4/1/05

Alpha blockers or alpha-adrenergic blockers

Cardura, Minipress, Hytrin, Doxaloc, Apa-Doxazosin, Gen-Doxazosin, Med-Doxazosin

ACE (angiotensin-Converting Enzyme) Inhibitors

Lotensin, Benicar, Capoten, Vasotec, Monopril, Prinivil, Zestril, Univasc, Aceon, Accupril Altace, Renormax, Mavik

Angiotensin-2-Receptor Antagonists, also known as ARBs

Atacand, Teveten, Avapro, Cozaar, Micardis, Diovan

Beta Blockers (Beta-Adrenergic-Blocking Drugs)

Sectral, Atenolol, Tenormin, Kerlone, Zebeta, Ziac, Cartrol, Coreg, Normodyne, Trandate, Lopressor, Corgard, Levatol, Visken, Inderal, Blocadren

Calcium Blockers or Calcium-Channel-Blocking Drugs

Norvasc, Vascor, Cardizem, Tiazac, Plendil, DynaCirc, Cardene, Adalat CC, Procardia XL, Nimotop, Sular, Calan, Isoptin, Verelan

Thiazide Diuretics

Naturetin, Aquatag, Exna, Marazide, Diuril, Anhydron, Esidrix, HydroDiuril, Diucardin, Saluron, Enduron, Aquatensen, Renese, Metahydrin, Naqua

COPYRIGHT 2005 Center for Medical Consumers, Inc.
COPYRIGHT 2005 Gale Group

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