Metohexal

Metoprolol is a selective beta₁ receptor blocker used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor® by Novartis, and Toprol® (in the USA), Seleken® or Selokeen® (elsewhere) by AstraZeneca and as Corvitol® by Berlin-Chemie AG. more...

It should be noted that Lopressor® refers to metoprolol tartrate, while Toprol® refers to metoprolol succinate.

Properties:

• Cardioselective
• Lipophilic
• Without intrinsic sympathomimetic activity (ISA)
• Without membrane stabilizing activity
• Short half-life must be taken at least twice daily or SR preparations

Indications:

• Essential hypertension
• Arrhythmias
• Coronary heart disease (prevention of angina attacks)
• Secondary prevention after a myocardial infarction
• Low dosed treatment of some forms of heart failure (see MERIT-HF study¹)
• Migraine prophylaxis
• Adjunct in treatment of hyperthyroidism

In the United States and most other countries, this medication is available only by prescription.

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