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Myoglobinuria

Myoglobinuria is the presence of myoglobin in the urine, usually associated to rhabdomyolysis or muscle destruction. Myoglobin is present in muscle cells as a reserve of oxygen. Trauma, vascular problems, venoms, certain drugs and other situations can destroy or damage the muscle releasing myoglobin to the circulation and thus to the kidneys. Under ideal situations myoglobin will be filtered and excreted with the urine, but if too much myoglobin is released into the circulation or in case of renal problems, it can occlude the renal filtration system leading to acute tubular necrosis and acute renal insufficiency.

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Necessity of myoglobinuria test.(Answering your questions) : An article from: Medical Laboratory Observer $5.95

Necessity of myoglobinuria test
Q We would like to discontinue offering the lab test for myoglobinuria. Has this test been replaced by other tests such as serum creatine kinase (CK) ...
From Medical Laboratory Observer, 9/1/05 by Frank Cruz, III
Pathologic quiz case: A man with exertion-induced cramps and myoglobinuria-pathologic diagnosis: McArdle disease (glycogenosis Type V or myophosphorylase
A 51-year-old man had a long-standing history of recurrent exertion-induced cramps and myoglobinuria. While growing up, he had never been able to participate ...
From Archives of Pathology & Laboratory Medicine, 9/1/03 by Getachew, Eskender
Renal failure secondary to acute tubular necrosis : epidemiology, diagnosis, and management
Acute tubular necrosis (ATN) is a form of acute renal failure (ARF) that is common in hospitalized patients. In critical care units, it accounts for ...
From CHEST, 10/1/05 by Namita Gill
Creatine kinase test
The creatine kinase test measures the blood levels of certain muscle and brain enzyme proteins.
From Gale Encyclopedia of Medicine, 4/6/01 by Richard Robinson
Alcohol-related neurologic disease
Alcohol, or ethanol, is a poison with direct toxic effects on nerve and muscle cells. Depending on which nerve and muscle pathways are involved, alcohol ...
From Gale Encyclopedia of Medicine, 4/6/01 by Laurie L. Barclay
Heel and calf capillary-support: pressure in lithotomy positions
A THREE-PART ANALYSIS was undertaken to increase understanding of the occurrence of pressure ulcers in lithotomy positions. An innovative measuring ...
From AORN Journal, 4/1/05 by Rebecca A. Roeder
Urinalysis: a comprehensive review
A complete urinalysis includes physical, chemical, and microscopic examinations. Midstream clean collection is acceptable in most situations, but the ...
From American Family Physician, 3/15/05 by Jeff A. Simerville
Rhabdomyolysis associated with quinacrine therapy in a patient with chronic cutaneous lupus erythematosus
Abstract We describe a patient who developed rhabdomyolysis 6 weeks after starting combination therapy with hydroxychloroquine and quinacrine for the treatment of chronic cutaneous lupus erythema
From Journal of Drugs in Dermatology, 3/1/05 by Naomi Creel

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