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Orphenadrine

Orphenadrine is a drug used to treat muscle injuries and Parkinson's disease.

Reference

  • MedlinePlus Database information
  • PubChem Substance Summary: Orphenadrine National Center for Biotechnology.
  1. ^  Labout JJ, Thijssen C, Keijser GG, Hespe W. "Difference between single and multiple dose pharmacokinetics of orphenadrine hydrochloride in man." European Journal of Clinical Pharmacology. 1982;21(4):343-50. PMID: 7056281
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Drug challenge
From Nursing, 1/1/98 by Gever, Marcy Portnoff

You routinely administer combination drugs...but do you know what's in them? To find out, match each combination of ingredients in Section II with its correct name in Section I.

SECTION I

1. Septra DS (Glaxo Wellcome)

2. P^sub 6^E^sub 1^ (Alcon)

3. Marax (Pfizer)

4. Oxipor VHC (Whitehall)

5. Norgesic (3M Pharmaceuticals)

SECTION II

a. pilocarpine, 6%; epinephrine bitartrate, 1%

These eyedrops may be prescribed for glaucoma. Pilocarpine, a direct-acting myotic, and epinephrine bitartrate, a sympathomimetic, decrease intraocular pressure. Warn your patient that this medication may impair his night vision.

b. orphenadrine, 25 mg; aspirin, 385 mg; caffeine, 30 mg

This drug may be prescribed to relieve pain caused by musculoskeletal disorders. Orphenadrine is a centrally acting muscle relaxant; aspirin, a nonopioid analgesic. Caffeine may enhance aspirin's analgesic effects. Tell your patient that this combination can cause a dry mouth and blurred vision.

c. theophylline, 130 mg; ephedrine sulfate, 25 mg; hydroxyzine HCl, 10 mg

This tablet may be prescribed to control asthma symptoms. Theophylline is a xanthine bronchodilator. Ephedrine sulfate relieves bronchial congestion. Hydroxyzine HCl, a sedating antihistamine, counters ephedrine sulfate's stimulant effects. Tell your patient to take this drug with meals.

d. sulfamethoxazole, 800 mg; trimethoprim, 160 mg

This combination may be prescribed to treat a urinary tract infection. Sulfamethoxazole is a sulfonamide antibiotic; trimethoprim is an anti-infective that suppresses bacterial growth. Tell your patient to take the medication until it's gone; stopping early may cause a relapse.

e. coal tar solution, 48.5%; salicylic acid, 1%; benzocaine, 2%

This nonprescription lotion may be used to treat psoriasis. Coal tar relieves itching; salicylic acid promotes skin sloughing and exposes new skin layers. Benzocaine is an anesthetic. Tell your patient that this lotion may temporarily discolor light-colored or bleached hair and may stain clothing. Warn him to avoid sun exposure to prevent photosensitivityreactions.

Copyright Springhouse Corporation Jan 1998
Provided by ProQuest Information and Learning Company. All rights Reserved

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