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Synovial sarcoma

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Introduction

A synovial sarcoma is one of the rarer types of soft-tissue sarcomas. It is usually found in either the legs or the arms. It usually starts near a major joint in the limb, but, more rarely, it can occur in the neck or torso. It affects more older adolescents and young adults than other age groups, and slightly more men than women.

Causes

Current medical research had not identified a cause as of yet.

Symptoms

Since this is a relatively rare type of cancer, large studies haven't been conducted, but, from the number of cases reported, there is usually a swelling around the affected area, and often there is pain or discomfort (however, some patients can have no pain or discomfort at all). The diagnosis of a synovial sarcoma is by biopsy.

Treatment

Treatment usually involves:

  • Medical surgery, to remove the cancer and a margin of healthy tissue.
  • Chemotherapy, (for example, Doxorubicin hydrochloride and Ifosfamide), to reduce the number of remaining microscopic cancer cells.
  • Radiotherapy to reduce the chances of local recurrence.

Scans to undertaken before, during, and after treatment

Various scanning techniques can be used to further localise and identify this cancer:

  • X-ray
  • CT
  • MRI

During treatment, the patient may have Bone Density Scans, to measure the impact of the chemotherapy on the skeleton.

Read more at Wikipedia.org


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Biphasic synovial sarcoma of the posterior pharyngeal wall: a case report. : An article from: Ear, Nose and Throat Journal $5.95 Synovial sarcoma: Histologic features and prognosis (Acta orthopaedica scandinavica : supplementum)

Synovial sarcoma of the pharynx: A case report - Original Article - Brief Article
Synovial sarcoma of the pharynx: A case report. (Original Article).
Biphasic synovial sarcoma of the posterior pharyngeal wall: a case report
Abstract Synovial sarcoma is not common in the head and neck region. Because its histopathologic features are many and varied, it is often misdiagnosed.
Monophasic Synovial Sarcoma of the Liver
We report a hepatic monophasic synovial sarcoma in a 60-year-old woman who presented with right upper quadrant pain subsequent to an intrahepatic bleed ...
Primary Renal Synovial Sarcoma Confirmed by Cytogenetic Analysis: A Lesion Distinct From Sarcomatoid Renal Cell Carcinoma
Primary synovial sarcoma rarely originates in the renal parenchyma. When this occurs, origin of this unusual tumor type has been the subject of debate ...
Synovial sarcoma with rhabdoid features
A 13-year-old white girl presented with a soft-tissue mass on the volar aspect of her proximal right forearm of 1-month duration. Magnetic resonance imaging ...
Primary pleural synovial sarcoma: A case report and review of the literature
Synovial sarcoma (SS) is an uncommon soft tissue tumor that occurs primarily in the extremities of young adults, especially in the periarticular region.
Synovial cell sarcoma
Synovial cell sarcoma frequently presents as a painful periarticular mass in the lower extremity of a young male patient. The mass may appear encapsulated ...
Malignant peripheral nerve sheath tumor with a t(X;18): A synovial sarcoma variant?
We describe an ankle tumor arising in a 16-year-old girl. The tumor demonstrated histology typical of a malignant peripheral nerve sheath tumor (MPNST), ...

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