Testotoxicosis
Familial male precocious puberty (also known as testotoxicosis) is a form of gonadotropin-independent precocious puberty in which boys experience early onset and progression of puberty. Signs of puberty can develop as early as an age of 1 year.
The final length of boys may be short due to a rapid advance in epiphyseal maturation. It is an autosomal recessive condition with a mutation of the LH receptor. Treatment is with drugs that suppress gonadal steroidogenesis, such as cyproterone acetate, ketoconazole or spironolactone and testolactone.
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Candidiasis
