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Valproate semisodium

Valproate semisodium (INN) or divalproex sodium (USAN) consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form. It is used in UK and US for the treatment of the manic episodes of bipolar disorder, and in the US for the treatment of epilepsy and migraine headaches. Its chemical name is sodium hydrogen bis(2-propylpentanoate). The extended release formulation allows for a single daily dose. more...

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Formulations

US

  • Tablets – Depakote® by Abbott Laboratories.

UK

  • Tablets – Depakote® by Sanofi-Aventis.

Canada

  • Tablets – Epival® by Abbott Laboratories. Generic formulations include Novo-Divalproex

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