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Blue rubber bleb nevus

Blue rubber bleb nevus syndrome (or "BRBNS", or "blue rubber bleb syndrome, or "blue rubber-bleb nevus", or "Bean's syndrome") is a rare disorder that consists mainly of abnormal blood vessels affecting the gastrointestinal tract. more...

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It causes several cavernous-type hemangiomas and has a potential for serious or fatal bleeding. Lesions are most commonly found in the small intestine and distal large bowel. The causes of this syndrome are unknown. Not more than a few hundred cases have been described worldwide.

It was first described by Gascoyen in 1860. In 1958 William Bennett Bean described the lesions further and came up with the term BRBNS, chosen because the 'cutaneous hemangiomas have the look and feel of rubber nipples'.

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Blue Rubber Bleb Nevus Syndrome - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References $28.95

Blue rubber bleb nevus syndrome : endobronchial involvement presenting as chronic cough - selected reports
This case report describes a rare presentation of chronic cough secondary to endobronchial involvement with blue rubber bleb nevus syndrome (BRBNS) lesions. BRNBS is a rare syndrome characterized w
From CHEST, 8/1/03 by Laura K. Gilbey
Blue rubber bleb nevus syndrome: A case report with long-term follow-up
Blue rubber bleb nevus syndrome is an uncommon condition manifested by gastrointestinal and skin hemangiomas that lead to gastrointestinal bleeding and ...
From Military Medicine, 8/1/01 by Place, Ronald J
Hemothorax and hemopericardium in a patient with Bean's blue rubber bleb nevus syndrome
David Langleben, M.D.;([unkeyable]) Norman Wolkove M.D., F.C.C.P.; Herbert Srolovitz, M.D.; Robin C. Billick, M.D.; and Nathan M. Sheiner, M.D. A patient with Bean's blue rubber bleb nevus syndro
From CHEST, 6/1/89 by David Langleben
Cavernous hemangioma of spermatic cord: Report of a case with immunohistochemical study
We present a case of spermatic cord cavernous hemangioma. A 32-year-old man presented with a circumscribed, painless mass in the left side of the spermatic ...
From Archives of Pathology & Laboratory Medicine, 3/1/02 by Liokumovich, Pavel
Causes of Occult and Obscure Gastrointestinal Bleeding
It is common for patients to present with occult or obscure gastrointestinal bleeding, but meaningful diagnostic criteria have not been delineated for ...
From American Family Physician, 6/1/00 by Richard Sadovsky
Diagnosis and treatment of cutaneous vascular lesions
Cutaneous vascular lesions are the most common pediatric birthmarks. Flat vascular malformations tend to persist, but raised vascular lesions, known as ...
From American Family Physician, 2/15/98 by Fern A. Wirth

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