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ICF syndrome

In medicine, immunodeficiency, centromere instability and facial anomalies syndrome (ICF syndrome) is a very rare recessive autosomal disorder.

It is characterized by variable reductions in serum immunoglobulin levels which cause most ICF patients to succumb to infectious diseases before adulthood. ICF syndrome patients exhibit facial anomalies which include hypertelorism, low-set ears, epicanthal folds and macroglossia.

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Abbreviations
From Social Security Bulletin, 1/1/03

COPYRIGHT 2003 Social Security Administration
COPYRIGHT 2004 Gale Group

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