X-ray of Paget's disease
Find information on thousands of medical conditions and prescription drugs.

Osteitis deformans

Paget's disease, otherwise known as osteitis deformans, is a chronic disorder that typically results in enlarged and deformed bones. It is named after Sir James Paget, the British surgeon who first described this disease. The excessive breakdown and formation of bone tissue that occurs with Paget's disease can cause bone to weaken, resulting in bone pain, arthritis, deformities, and fractures. Paget's disease may be caused by a slow virus infection, present for many years before symptoms appear. There is also a hereditary factor since the disease may appear in more than one family member. more...

Home
Diseases
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
Obesity
Obsessive-compulsive...
Occipital horn syndrome
OCD
Ochronosis
Oculocutaneous albinism,...
Oculopharyngeal muscular...
Odontophobia
Odynophobia
Oikophobia
Olfactophobia
Olivopontocerebellar atrophy
Omenn syndrome
Onchocerciasis
Oncocytoma
Ondine's curse
Opportunistic infections
Oppositional defiant...
Optic atrophy
Optic neuritis
Oral leukoplakia
Ornithosis
Orthostatic intolerance
Osgood-Schlatter disease
Osteitis deformans
Osteoarthritis
Osteochondritis
Osteochondritis dissecans
Osteochondroma
Osteogenesis Imperfecta
Osteomalacia
Osteomyelitis
Osteopetrosis, (generic...
Osteoporosis
Osteosclerosis
Otosclerosis
Otospondylomegaepiphyseal...
Ovarian cancer
P
Q
R
S
T
U
V
W
X
Y
Z
Medicines

Paget's disease is rarely diagnosed in people under 40 years of age. Men and women are affected equally. Prevalence of Paget's disease ranges from 1.5 to 8 percent depending on age and country of residence. Prevalence of familial Paget's disease (where more than one family member has the disease) ranges from 10 to 40 percent in different parts of the world. Because early diagnosis and treatment is important, after age 40, siblings and children of someone with Paget's disease may wish to have an alkaline phosphatase blood test every 2 or 3 years. If the alkaline phosphatase level is above normal, other tests such as a bone-specific alkaline phosphatase test, bone scan, or x-ray can be performed.

Symptoms

Many patients do not know they have Paget's disease because they have a mild case with no symptoms. Sometimes, symptoms may be confused with those of arthritis or other disorders. In other cases, the diagnosis is made only after complications have developed. Symptoms can include:

  • Bone pain is the most common symptom. Bone pain can occur in any bone affected by Paget's disease. It often localizes to areas adjacent to the joints.
  • Headaches and hearing loss may occur when Paget's disease affects the skull.
  • Pressure on nerves may occur when Paget's disease affects the skull or spine.
  • Increased head size, bowing of limb, or curvature of spine may occur in advanced cases.
  • Hip pain may occur when Paget's disease affects the pelvis or thighbone.
  • Damage to cartilage of joints may lead to arthritis.

Diagnosis

Paget's disease may be diagnosed using one or more of the following tests:

  • Pagetic bone has a characteristic appearance on x-rays.
  • An elevated level of alkaline phosphatase in the blood can be suggestive of Paget's disease.
  • Bone scans are Useful in determining the extent and activity of the condition. If a bone scan suggests Paget's disease, the affected bone(s) should be x-rayed to confirm the diagnosis.

Prognosis

The outlook is generally good, particularly if treatment is given before major changes in the affected bones have occurred. Any bone or bones can be affected, but Paget's disease occurs most frequently in the spine, skull, pelvis, thighs, and lower legs. In general, symptoms progress slowly, and the disease does not spread to normal bones. Treatment can control Paget's disease and lessen symptoms but is not a cure. Osteogenic sarcoma, a form of bone cancer, is an extremely rare complication that occurs in less than one percent of all patients.

Other medical conditions

Paget's disease may lead to other medical conditions, including:

Read more at Wikipedia.org


[List your site here Free!]


Skull x rays
From Gale Encyclopedia of Medicine, 4/6/01 by Teresa G. Norris

Definition

Skull x rays are performed to examine the nose, sinuses, and facial bones. These studies may also be referred to as sinus x rays. X-ray studies produce films, also known as radiographs, by aiming x rays at soft bones and tissues of the body. X-ray beams are similar to light waves, except their shorter wavelength allows them to penetrate dense substances, producing images and shadows on film.

Purpose

Doctors may order skull x rays to aid in the diagnosis of a variety of diseases or injuries.

Sinusitis

Sinus x rays may be ordered to confirm a diagnosis of sinusitis, or sinus infection.

Fractures

A skull x ray may detect bone fractures resulting from injury or disease. The skull x ray should clearly show the skull cap, jaw bones, and facial bones.

Tumors

Skull radiographs may indicate tumors in facial bones, tissues, or the sinuses. Tumors may be benign (not cancerous) or malignant (cancerous).

Other

Birth defects (referred to as congenital anomalies) may be detected on a skull x ray by changes in bone structure. Abnormal tissues or glands resulting from various conditions or diseases may also be shown on a skull radiograph.

Precautions

As with any x-ray procedure, women who may be pregnant are advised against having a skull x ray if it is not absolutely necessary. However, a lead apron may be worn across the abdomen during the procedure to protect the fetus. Children are also more sensitive to x-ray exposure. Children of both sexes should wear a protective covering (a lead apron) in the genital/reproductive area. In general, skull x-ray exposure is minimal and x-ray equipment and procedures are monitored to ensure radiation safety.

Description

Skull or sinus x rays may be performed in a doctor's office that has x-ray equipment and a technologist available. The exam may also be performed in an outpatient radiology facility or a hospital radiology department.

In many instances, particularly for sinus views, the patient will sit upright in a chair, perhaps with the head held stable by a foam vise. A film cassette is located behind the patient. The x-ray tube is in front of the patient and may be moved to allow for different positions and views. A patient may also be asked to move his or her head at various angles and positions.

In some cases, technologists will ask the patient to lie on a table and will place the head and neck at various angles. In routine skull x rays, as many as five different views may be taken to allow a clear picture of various bones and tissues. The length of the test will vary depending on the number of views taken, but in general, it should last about 10 minutes. The technologist will usually ask a patient to wait while the films are being developed to ensure that they are clear before going to the radiologist.

Preparation

There is no preparation for the patient prior to arriving at the radiology facility. Patients will be asked to remove jewelry, dentures, or other metal objects that may produce artifacts on the film. The referring doctor or x-ray technologist can answer any questions regarding the procedure. Any woman who is, or may be, pregnant should tell the technologist.

Aftercare

There is no aftercare required following skull or sinus x-ray procedures.

Risks

There are no common side effects from skull or sinus x ray. The patient may feel some discomfort in the positioning of the head and neck, but will have no complications. Any x-ray procedure carries minimal radiation risk, and children and pregnant women should be protected from radiation exposure to the abdominal or genital areas.

Normal results

Normal results should indicate sinuses, bones, tissues, and other observed areas are of normal size, shape, and thickness for the patient's age and medical history. Results, whether normal or abnormal, will be provided to the referring doctor in a written report.

Abnormal results

Abnormal results may include:

Sinusitis

Air in sinuses will show up on a radiograph as black, but fluid will be cloudy or white (opaque). This helps the radiologist to identify trapped fluids in the sinuses. In chronic sinusitis, the radiologist may also note thickening or hardening of the bony wall of an infected sinus.

Fractures

Radiologists may recognize even tiny facial bone fractures as a line of defect.

Tumors

Tumors may be visible if the bony sinus wall is distorted or destroyed. Abnormal findings may result in follow-up imaging studies.

Other

Skull x rays may also detect disorders that show up as changes in bone structure, such as Paget's disease of the bone or acromegaly (a disorder associated with excess growth hormones from the pituitary gland). Areas of calcification, or gathering of calcium deposits, may indicate a condition such as an infection of bone or bone marrow (osteomyelitis).

Key Terms

Radiograph
The actual picture or film produced by an x-ray study.
X ray
A form of electromagnetic radiation with shorter wavelengths than normal light. X rays can penetrate most structures.

Further Reading

For Your Information

    Books

  • Illustrated Guide to Diagnostic Tests, edited by D. Weinstock, et al. Springhouse, PA: Springhouse Corporation, 1998.

    Organizations

  • Cancer Information Clearinghouse, National Cancer Institute. Building 31, Room 10A24, 9000 Rockville Pike, Bethesda, MD 20892. (800) 4-Cancer. http://www.nci.nih.gov.
  • The National Head Injury Foundation, Inc. 1140 Connecticut Ave. NW, Suite 812, Washington, DC 20036. (800) 444-NHIF.
  • Radiological Society of North America. 2021 Spring Rd., Suite 600, Oak Brook, IL 60521-1860. (708) 571-2670. http://www.rsna.org.

Gale Encyclopedia of Medicine. Gale Research, 1999.

Return to Osteitis deformans
Home Contact Resources Exchange Links ebay