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Van der Woude syndrome

Van Der Woude syndrome consists of the following characteristics: cleft lip and palate, missing teeth and lip pits.

Cause

It is caused by mutations in the IRF6 gene. (Popliteal pterygium syndrome is also caused by mutations in this gene.)

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Scientists Identify Key Gene Involved in Cleft Lip and Palate
From National Institutes of Health, 10/1/02 by Bob Kuska
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