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Retroperitoneal fibrosis

Retroperitoneal fibrosis or Ormond's disease is a disease featuring the proliferation of fibrous tissue in the retroperitoneum, the compartiment of the body containing the kidneys, aorta, renal tract and various other structures. more...

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Medicines

It may present with lower back pain, renal failure, hypertension, deep vein thrombosis and other obstructive symptoms.

Its association with various immune-related conditions and response to immunosuppression have led to speculations as to the autoimmune etiology of idiopathic RPF. One-third of the cases are secondary to malignancy, medication (methysergide, hydralazine, beta blockers), aortic aneurysm or certain infections.

Treatment is generally with glucocorticoids initially, followed by DMARDs either as steroid-sparing agents or if refractory on steroids. The SERM tamoxifen has shown to improve the condition in various small trials, although the exact mechanism of its action remains unclear.

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Retroperitoneal fibrosis
Retroperitoneal fibrosis, an uncommon and ill-defined condition, has a variety of causes and presenting features. The fibrotic process often produces ureteral obstruction and compression of surroundi
Amyloid A gastrointestinal amyloidosis-associated with idiopathic retroperitoneal fibrosis: Report of a rare autopsy case and review of the literature
We report a rare autopsy case of secondary gastrointestinal amyloid A (AA) amyloidosis associated with idiopathic retroperitoneal fibrosis (IRF) in a 67-year-old woman. Masses were identified aroun
Persistent Pneumomediastinum in Interstitial Fibrosis Associated With Rheumatoid Arthritis - )
Treatment With High-Concentration Oxygen We present a case of persistent spontaneous pneumomediastinum precipitated by an upper respiratory infection ...
Mediastinal Fibrosis Is Associated With Human Leukocyte Antigen-A2 - )
Objective: To determine the association between mediastinal fibrosis and human leukocyte antigen (HLA) genes. Design: Case-control study. Setting: ...
Unilocular retroperitoneal cyst of mesothelial origin presenting as renal mass: A report of 2 cases
We report the first 2 cases, to our knowledge, of retroperitoneal cysts with features of mesothelial differentiation that clinically mimic renal masses.
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