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Wolfram syndrome

Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), is a rare genetic disorder, causing diabetes mellitus, optic atrophy, and deafness. It was first diagnosed in 1938 by a physician named Wolfram in four siblings. The disease affects both the brain (especially the brain stem) and the central nervous system. It is thought to be caused by both a malfunction of the mitochondria and of myelination, the latter in effect similar to multiple sclerosis. There is no known treatment. more...

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Life expectancy of people suffering from this syndrome is about 30 years.

See also : List of rare diseases

Read more at Wikipedia.org


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