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Xenical

Orlistat (marketed as Xenical by Roche) is a drug designed to treat obesity. It works by inhibiting pancreatic lipase, an enzyme that breaks down fat in the intestine. Without this enzyme, fat from the diet is excreted undigested, and not absorbed by the body. more...

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Orlistat is available on prescription, although, as with many prescription drugs, it is possible to obtain it from online pharmacies. In 2004, a lower-dose version of the drug (60 mg compared to 120 mg for the prescription dose) was released over the counter in Australia and New Zealand; the United States is expected to follow in the near future.

It has a number of side effects related to digestion. Because its main effect is to prevent dietary fat from being absorbed from the gut, the fat is excreted and so the stool becomes oily, runny, and gassy. Bowel movements may become frequent, urgent or uncontrollable. To minimize these effects, the fat content of the diet should be reduced to about 30%. Obviously many patients find these side effects uncomfortable, and this has resulted in serious compliance issues.

The drug should only be taken when there is fat in a meal (it will not work if there is no fat in the diet). Because some vitamins are fat soluble, the effect of Orlistat is to reduce their absorption. A multivitamin tablet containing these vitamins (D E K and beta-carotene) should be taken once a day, at least 2 hours before or after taking the drug.

The amount of weight loss achieved with Orlistat is quite modest. The weight loss in a 4-year double-blind trial averaged only 2.8 kilograms (about 6 pounds) more than placebo. Despite this cosmetically small effect, there was a 37% reduction in the incidence of diabetes, a medically very significant difference.

You must not take Xenical if you:

  • have problems absorbing food
  • have reduced gallbladder function
  • are pregnant, or are still breast-feeding (it is not known whether Xenical is expressed in breast milk)
  • have certain kidney problems (consult your doctor).

Read more at Wikipedia.org


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The Xenical Advantage : How To Use the Remarkable New FDA-Approved Drug to Lose Weight Faster - and Keep It Off -- Safely and Effectively $1.25 Xenical - A Medical Dictionary Bibliography and Annotated Research Guide to Internet References $32.71
Xenical. : An article from: Family Practice News $5.95 Caution Advised for 'Xen-Phen' Diet Drug Combo.(Xenical, phentermine) : An article from: Family Practice News $5.95
Meridia and Xenical promos target physicians : An article from: Medical Marketing and Media $10.00 Two Weight Loss Drugs-Meridia and Xenical The Pros and Cons of Each : An article from: HealthFacts $10.00
Is Xenical for you? : An article from: Joe Weider's Shape $3.00 New & approved: Xenical, Triaz Acne Pads.(Clinical Rounds) : An article from: Pediatric News $5.95
LA SALUD.(TT: Health.)(Artículo Breve) : An article from: Contenido $5.95 Xenical offers "buy 3 get 3 free" plan : An article from: Medical Marketing and Media $10.00

Two weight loss drugs—Meridia and Xenical the pros and cons of each
Thinking of taking a weight loss drug? Now that the popular dietary supplement ephedra has been linked to sudden cardiac death and is due to be removed ...
Roche. - Reporter's Notebook - Gets FDA approval to treat obesity in adolescents with its prescription weight-loss medication Xenical orlistat - Brief
Roche last month received FDA approval to treat obesity in adolescents with its prescription weight-loss medication Xenical (orlistat), the first approval ...
Roche's prescription weight-loss drug Xenical® - orlistat - Brief Article
Roche's prescription weight-loss drug Xenical[R] (orlistat) has proven effective in helping to control diabetes. The drug helps control blood glucose ...
NCPA joins Hoffmann-La Roche educational program - marketing Xenical, weight loss drug - Brief Article
The National Community Pharmacists Association has joined with Hoffmann-La Roche to offer compliance and educational support to patients taking the prescription ...
Snda Filed For Xenical As Type 2 Diabetes Treatment Option
Roche, Mississauga, ON, Canada, has announced that a supplemental New Drug Application (sNDA) has been submitted to the U.S. Food and Drug Administration ...
First Canadian Trial For Xenical Launched
Hoffmann-La Roche Limited, Canada, has initiated a clinical trial to evaluate its weight loss medication Xenical(R) (orlistat) in overweight adolescents.
The doctor is in
Donald Hensrud, M.D., editor in chief of Mayo Clinic Healthy Weight for EveryBody (Mayo Foundation for Medical Education and Research, 2005), weighs ...
Roche commits $75M to Xenical DTC campaign
Hoffman-La Roche has begun its $75 million direct-to-consumer campaign for Xenical (orlistat), one of the largest DTC spends in the industry. Of the ...

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