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Follicular lymphoma

Follicular lymphoma (FL) is the most common of the indolent non-Hodgkin's lymphomas. It is defined as a lymphoma of follicle center B-cells (centrocytes and centroblasts), which has at least a partially follicular pattern. more...

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Morphology

The tumor is composed of follicle center cells, usually a mixture of centrocytes (cleaved follicle center cells, "small cells") and centroblasts (large noncleaved follicle center cells, "large cells"). Centrocytes typically predominate; centroblasts are usually in the minority, but by definition are always present. Rare lymphomas with a follicular growth pattern consist almost entirely of centroblasts. Occasional cases may show plasmacytoid differentiation or foci of marginal zone or monocytoid B-cells.

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Lymphoma; methods and protocols
From SciTech Book News, 9/1/05

Lymphoma; methods and protocols.

Ed. by Timothy Illidge & Peter W.M. Johnson.

Humana Press Inc.

2005

342 pages

$125.00

Hardcover

Methods in molecular medicine; 115

RC280

Mostly British scientists offer some practical information on the current molecular approaches being used to understand, classify, and treat lymphoma. The volume is not exhaustive for every chromosomal translocation and gene rearrangement, of course, but is designed to provide a background to the field and a foundation for the molecular diagnostics of a group of disease that are both biologically interesting and medically important. The topics include the purification of primary malignant B-cells and immunoblot analysis of Bcl-2 family proteins, idiotype gene rescue in follicular lymphoma, and antibody techniques used to study anaplastic lymphoma kinase-positive ALCL.

([c] 2005 Book News, Inc., Portland, OR)

COPYRIGHT 2005 Book News, Inc.
COPYRIGHT 2005 Gale Group

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