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Sensorineural hearing loss

Sensorineural hearing loss is a type of hearing loss in which the root cause lies in the vestibulocochlear nerve (Cranial nerve VIII), the inner ear, or central processing centers of the brain.
The Weber test, in which a tuning fork is touched to the head, localizes to the normal ear in people with this condition. The Rinne test, which tests air conduction vs. bone conduction is positive (normal), though both bone and air conduction are reduced equally. more...

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Medicines

Sudden sensorineural hearing loss is an otologic emergency, and must be treated with a high dose of steroids.

Differential diagnosis

Sensorineural hearing loss may be congenital or acquired.

Congenital

  • lack of development (aplasia) of the cochlea
  • Chromosomal syndromes (rare)
  • Congenital cholesteatoma - squamous epithelium from the ear canal invades the middle ear, which is normally covered by respiratory epithelium. The squamous epithelium behaves like an invasive tumour and destroys middle ear structures if not removed
  • Delayed familial progressive

Acquired

  • Inflammatory
    • Suppurative labyrinthitis
    • Meningitis
    • Mumps
    • Measles
    • Viral
    • Syphilis
  • Ototoxic drugs
    • Aminoglycosides (most common cause; e.g., tobramycin)
    • Loop diuretics (e.g., Furosemide)
    • Anti-Metabolites (e.g., Methotrexate)
    • Salicylates (e.g., Aspirin)
  • Physical trauma - either due to a fracture of the temporal bone affecting the cochlea and middle ear, or a shearing injury affecting cranial nerve VIII.
  • Noise-induced - prolonged exposure to loud noises (>90dB) causes hearing loss which begins at 4000Hz (high frequency). The normal hearing range is from 125 Hz to 8,000 Hz.
  • Presbyacusis - age-related hearing loss that occurs in the high frequency range (4000Hz to 8000Hz).
  • Sudden hearing loss
    • Idiopathic
    • Vascular ischemia of the inner ear or CN 8
    • Perilymph fistula, usually due to a rupture of the round or oval windows and the leakage of perilymph. The patient will most likely also experience vertigo or imbalance. A history of an event that increased intracranial pressure or caused trauma is usually present).
  • Autoimmune - a prompt injection of steroids into ear is necessary.
  • Cerebellopontine angle tumour (junction of the pons and cerebellum) (the cerebellopontine angle is the exit site of both CN7 and CN8. Patients with these tumours often have signs and symptoms corresponding to compression of both nerves)
    • Acoustic neuroma (Vestibular schwannoma) - this is a schwannoma (benign neoplasm of Schwann cells)
    • Meningioma - benign tumour of the pia and arachnoid maters
  • Meniere's disease - causes sensorineural hearing loss in the low frequency range (125 Hz to 1000 Hz). Meniere's disesase is characterized by sudden attacks of vertigo lasting minutes to hours preceded by tinnitus, aural fullness, and fluctuating hearing loss.


Table 1. A table comparing sensorineural to conductive hearing loss

Read more at Wikipedia.org


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Magnesium treatment for sudden hearing loss
From Alternative Medicine Review, 12/1/04 by B.I. Nageris

Nageris BI, Ulanovski D, Attias J. Ann Otol Rhilol Laryngol 2004;113:672-675.

Magnesium treatment has been repeatedly shown to reduce the incidence of both temporary and permanent noise-induced hearing loss. We hypothesized that it might also improve the permanent threshold shift in patients with acute-onset hearing loss. In a prospective, randomized, double-blind, placebo-controlled trial, 28 patients with idiopathic sudden sensorineural hearing loss were treated with either steroids and oral magnesium (study group) or steroids and a placebo (control group). Compared to the controls, the magnesium-treated group had a significantly higher proportion of patients with improved hearing (>10 dB hearing level) across all frequencies tested, and a significantly greater mean improvement in all frequencies. Analysis of the individual data confirmed that more patients treated with magnesium experienced hearing improvement, and at a larger magnitude, than control subjects. Magnesium is a relatively safe and convenient adjunct to steroid treatment for enhancing the improvement in hearing, especially in the low-tone range, in patients with sudden sensorineural hearing loss.

COPYRIGHT 2004 Thorne Research Inc.
COPYRIGHT 2005 Gale Group

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