Etoposide chemical structure
Find information on thousands of medical conditions and prescription drugs.

Etopophos

Etoposide phosphate (Eposin®, Etopophos®, Vepesid®, VP-16®) is an inhibitor of the enzyme topoisomerase II. It is used as a form of chemotherapy for malignancies such as lung cancer, testicular cancer, lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme. It is often given in combination with other drugs. more...

Home
Diseases
Medicines
A
B
C
D
E
E-Base
Ecstasy (drug)
Edecrin
Edrophonium
Edrophonium chloride
Efavirenz
Effexor
Eflornithine
Elavil
Eldepryl
Elidel
Eligard
Elitek
Elixomin
Elixophyllin
Ellagic acid
Elmiron
Eloxatin
Elspar
Emtriva
Emylcamate
Enalapril
Enalaprilat
Enalaprilat
Endep
Enflurane
Enoxaparin sodium
Entacapone
Enulose
Epi-pen
Epinephrine
Epirubicin
Epitol
Epivir
Epogen
Eprosartan
Ergocalciferol
Ergoloid Mesylates
Ergotamine
Eryc
Eryped
Erythromycin
Esgic
Eskalith
Esmolol
Estazolam
Estazolam
Estrace
Estraderm
Estradiol
Estradiol
Estradiol valerate
Estring
Estrogel
Estrone
Estrostep
Ethacridine
Ethambutol
Ethchlorvynol
Ethosuximide
Ethotoin
Etiracetam
Etodolac
Etopophos
Etoposide
Etorphine
Evista
Exelon
Exemestane
Hexal Australia
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z

Chemically it derives from podophyllotoxin, a toxin found in the American Mayapple.

It is given intravenously or by mouth in capsule form. If the drug is given by IV it must be done slowly over a 30 to 60 minute period because it can lower blood pressure as it is being administered. Blood pressure is checked often during infusing. The physician may lengthen or shorten the time depending on circumstances.

Side Effects

Common are:

  1. low blood pressure
  2. hair loss
  3. pain and or burning at the IV site
  4. constipation or diarrhea
  5. metallic food taste
  6. Bone marrow suppression, leading to
    1. decreased white blood cell counts (leading to increased susceptibility to infections)
    2. low red blood cell counts (anemia)
    3. low platelet counts (leading to easy bruising and bleeding)

Less common are:

  1. nausea and vomiting
  2. allergic type reactions
  3. rash
  4. fever, often occurring shortly after IV administration and not due to infection
  5. mouth sores

Instruction

Patients are generally advised to call their doctor in case of fever, symptoms of infection or painful injection sites, as these may progress severely without adequate medical attention.

It is advised to drink lots of fluids after treatment to prevent damage to the bladder and kidneys, typically 1.5 to 3.5 litres of water on the day of treatment and for several days after.

Read more at Wikipedia.org


[List your site here Free!]


Spector, Roseman & Kodroff, P.C. Say Federal Judge Allows Consumers to Continue Class Action for Overpayment of Medicare Part B Prescription Drugs
From Business Wire, 8/19/05

BOSTON -- In a national class action lawsuit filed by Spector, Roseman & Kodroff, P.C. on behalf of consumers and third party payors claiming prescription drug overpayments, U.S. District Judge Patti B. Saris indicated that she would certify a nationwide class of Medicare Part B beneficiaries, if enough consumers appeared and filed complaints by October 17, 2005.

According to Jeffrey L. Kodroff, one of the lead counsel for the plaintiffs in In re Pharmaceutical Industry Average Wholesale Price Litigation, "Judge Saris offered a clear roadmap for class certification to consumers covered by Medicare Part B who have overpaid for physician administered drugs manufactured by GlaxoSmithKline, Bristol-Meyers Squibb, AstraZeneca, Schering-Plough and Johnson & Johnson because the companies fraudulently created, manipulated and inflated the cost of prescription medication to consumers by overstating the average wholesale price." In case filings, Kodroff, from the Philadelphia-based law firm of Spector, Roseman & Kodroff, P.C., alleged that the defendants knowingly inflated the average wholesale price or AWP to cause beneficiaries of the Medicare Part B program, other consumer patients and third party payors to overpay for drugs used in treating cancer, rheumatoid arthritis and other chronic illnesses.

Kodroff said Judge Saris stated earlier this week that she would certify a nationwide class of Medicare Part B beneficiaries once the complaint is amended to add individual class representatives who pay all or a portion of their Medicare Part B co-payment for their drugs. At that time she also certified a Massachusetts statewide class for third party payors, offering supplemental insurance to cover Medicare Part B co-pays and a Massachusetts statewide class for any payments for brand name and generic drugs, outside of the Medicare Part B arena, if the reimbursement was explicitly based on average wholesale price.

The prescription drugs mentioned in this complaint include: Alkeran, Blenoxane, Cytoxan, Etopophos, Kytril, Navelbine, Paraplatin, Procrit, Remicade, Rubex, Taxol, Vepesid, Zofran, Zoladex and Zovirax.

For more information about this lawsuit, and to determine if you are eligible to participate in these actions, contact Jeffrey L. Kodroff or John A. Macoretta at Spector, Roseman & Kodroff, P.C. at 1-888-844-5862. For a copy of this order visit www.srk-law.com.

COPYRIGHT 2005 Business Wire
COPYRIGHT 2005 Gale Group

Return to Etopophos
Home Contact Resources Exchange Links ebay